Histone deacetylase 3 (HDAC3) inhibitors as anticancer agents: A review
Abstract Among different Histone deacetylases (HDACs), histone deacetylase 3 (HDAC3) is
an epigenetic drug target which is currently marked as a potential therapeutic strategy to …
an epigenetic drug target which is currently marked as a potential therapeutic strategy to …
Binary quantitative activity-activity relationship (QAAR) studies to explore selective HDAC8 inhibitors: In light of mathematical models, DFT-based calculation and …
Abstract Histone deacetylase 8 (HDAC8) selectivity over other HDACs is a major concern of
interest, since HDAC8 has been implicated as a potential drug target of many diseases …
interest, since HDAC8 has been implicated as a potential drug target of many diseases …
Quantitative activity–activity relationship (QAAR) driven design to develop hydroxamate derivatives of pentanoic acids as selective HDAC8 inhibitors: synthesis …
Histone deacetylase 8 (HDAC8) has been implicated as a potential drug target of many
diseases including cancer. HDAC8 isoform selectivity over other class-I HDACs is a major …
diseases including cancer. HDAC8 isoform selectivity over other class-I HDACs is a major …
Medicinal chemistry of histone deacetylase inhibitors
Today, we are witnessing an explosion of scientific concepts in cancer chemotherapy. It has
been considered for a long time that genetic instability in cancer should be treated with …
been considered for a long time that genetic instability in cancer should be treated with …