Regulation of formation, stemness and therapeutic resistance of cancer stem cells

N Jing, WQ Gao, YX Fang - Frontiers in Cell and Developmental …, 2021 - frontiersin.org
Over the past 20 years cancer stem cells (CSCs) have been proposed as key players in the
tumorigenesis and progression, which are closely related to the initiation, metastasis and …

Unveiling the influence of tumor microenvironment and spatial heterogeneity on temozolomide resistance in glioblastoma using an advanced human in vitro model of …

MSY Lam, JJY Aw, D Tan, R Vijayakumar, HYG Lim… - Small, 2023 - Wiley Online Library
Glioblastoma (GBM) is the most common primary malignant brain cancer in adults with a
dismal prognosis. Temozolomide (TMZ) is the first‐in‐line chemotherapeutic; however …

T‐bet Regulates Ion Channels and Transporters and Induces Apoptosis in Intestinal Epithelial Cells

L Chen, H Yi, Q Li, T Duan, X Liu, L Li… - Advanced …, 2024 - Wiley Online Library
T‐bet, encoded by TBX21, is extensively expressed across various immune cell types, and
orchestrates critical functions in their development, survival, and physiological activities …

Construction of a prognostic model related to copper dependence in breast cancer by single-cell sequencing analysis

X Guan, N Lu, J Zhang - Frontiers in Genetics, 2022 - frontiersin.org
Purpose: To explore the clinical significance of copper-dependent-related genes (CDRG) in
female breast cancer (BC). Methods: CDRG were obtained by single-cell analysis of the …

The Diagnostic and Prognostic Value of the Immune Checkpoint BGN in Thymoma

Y Liu, S Chen, Y Wang, Z Zhang, Z Wang, Z Tao… - Biochemical …, 2024 - Springer
Thymoma is frequently correlated with various autoimmune diseases. However, unequivocal
therapeutic targets for thymoma remain undefined, and the role of immune checkpoints in …

PHF20 is a Novel Prognostic Biomarker and Correlated with Immune Status in Breast Cancer

Z Chen, S Zhong, Z Zhang, J Tang - Biochemical genetics, 2023 - Springer
Increasing evidence has demonstrated that enhanced PHF20 expression plays a crucial
role in cancer development and progression. However, little is known about the prognostic …

WDR82-Mediated H3K4me3 Is Associated with Tumor Proliferation and Therapeutic Efficacy in Pediatric High-Grade Gliomas

N Wadhwani, S Nayak, Y Wang, R Hashizume, C Jie… - Cancers, 2023 - mdpi.com
Simple Summary Pediatric high-grade gliomas bearing either an H3G34V/R or H3K27M
mutation are incurable brain tumors with unique epigenomes. Current epigenomic studies …

Plant Homeodomain Finger Protein 20 (Phf20) And Its Homolog Phf20 Like 1 (Phf20L1) Define Two Distinct Non-Specific Lethal (Nsl) Complexes

H Van, HT Van - 2022 - digitalcommons.library.tmc.edu
Abstract Plant Homeodomain Finger Protein 20 (PHF20) and its homolog PHF20 Like 1
(PHF20L1) are known subunits of the Non-Specific Lethal (NSL) complex, which acetylates …