Immunohistochemical markers for distinguishing metastatic breast carcinoma from other common malignancies: update and revisit

Q Ding, L Huo, Y Peng, EC Yoon, Z Li… - Seminars in Diagnostic …, 2022 - Elsevier
Due to the high prevalence of breast cancer in the female, a metastasis from primary breast
cancer is usually considered in the differential diagnosis of metastatic carcinoma in the …

Cholangiocarcinoma: Pathologic and molecular classification in the era of precision medicine

P Gopal, ME Robert, X Zhang - Archives of Pathology & …, 2024 - meridian.allenpress.com
Context.—Cholangiocarcinoma (CCA) is a heterogeneous cancer of the bile duct, and its
diagnosis is often challenging. Objective.—To provide insights into state-of-the-art …

TRPS1, GATA3, and SOX10 expression in triple-negative breast carcinoma

EC Yoon, G Wang, B Parkinson, L Huo, Y Peng… - Human pathology, 2022 - Elsevier
A diagnostic dilemma can be encountered when primary triple-negative breast carcinoma
(TNBC) without an in situ component or metastatic TNBCs lose the currently used organ …

GeneFriends: gene co-expression databases and tools for humans and model organisms

P Raina, R Guinea, K Chatsirisupachai… - Nucleic Acids …, 2023 - academic.oup.com
Gene co-expression analysis has emerged as a powerful method to provide insights into
gene function and regulation. The rapid growth of publicly available RNA-sequencing (RNA …

TRPS1 expression in breast carcinomas: focusing on metaplastic breast carcinomas

B Parkinson, W Chen, T Shen… - The American journal of …, 2022 - journals.lww.com
TRPS1 has been recently demonstrated as a highly sensitive and specific marker for breast
carcinomas. To further explore TRPS1's utility in breast carcinoma, we systematically …

Expression of TRPS1 in phyllodes tumor and sarcoma of the breast

J Wang, WL Wang, H Sun, L Huo, Y Wu, H Chen… - Human Pathology, 2022 - Elsevier
When a sarcomatous neoplasm is identified in the breast, distinguishing metaplastic
carcinoma, malignant phyllodes tumor (MPT), and primary sarcoma is a diagnostic …

A stacked autoencoder based gene selection and cancer classification framework

M Gokhale, SK Mohanty, A Ojha - Biomedical Signal Processing and …, 2022 - Elsevier
Cancer is one of the most common causes of death worldwide and is, therefore, a prominent
area of biomedical research. Cancer is a genetic disease in which improperly functioning …

Matrix Gla protein (MGP), GATA3, and TRPS1: a novel diagnostic panel to determine breast origin

T Du, L Pan, C Zheng, K Chen, Y Yang, J Chen… - Breast cancer …, 2022 - Springer
Background Metastatic breast carcinoma is commonly considered during differential
diagnosis when metastatic disease is detected in females. In addition to the tumor …

Immunohistochemical expression of TRPS1 in mammary Paget disease, extramammary Paget disease, and their close histopathologic mimics

WC Cho, Q Ding, WL Wang… - Journal of cutaneous …, 2023 - Wiley Online Library
Background Trichorhinophalangeal syndrome type 1 (TPRS1) expression has been found to
be highly sensitive and specific for breast carcinomas. The frequency of TRPS1 expression …

Systematic elucidation and pharmacological targeting of tumor-infiltrating regulatory T cell master regulators

A Obradovic, C Ager, M Turunen, T Nirschl… - Cancer Cell, 2023 - cell.com
Due to their immunosuppressive role, tumor-infiltrating regulatory T cells (TI-Tregs)
represent attractive immuno-oncology targets. Analysis of TI vs. peripheral Tregs (P-Tregs) …