The budding yeast Saccharomyces cerevisiae is a well-characterized and popular model
system for investigating histone modifications and the inheritance of chromatin states. The …

The kinetochore is a mega-dalton protein assembly that forms within centromeric regions of
chromosomes and directs their segregation during cell division. Here we review cell cycle …

Restricting the localization of the histone H3 variant CENP-A (Cse4 in yeast, CID in flies) to
centromeres is essential for faithful chromosome segregation. Mislocalization of CENP-A …

Faithful chromosome segregation maintains chromosomal stability as errors in this process
contribute to chromosomal instability (CIN), which has been observed in many diseases …

The loading and maintenance of centromeric histone 3 (CENH3) at the centromere are
critical processes ensuring appropriate kinetochore establishment and equivalent …

Centromeric localization of evolutionarily conserved CENP-A (Cse4 in Saccharomyces
cerevisiae) is essential for chromosomal stability. Mislocalization of overexpressed CENP-A …

The kinetochore, a multi-protein complex assembled on centromeres, is essential to
segregate chromosomes during cell division. Deficiencies in kinetochore function can lead …

The use of algal biomass for biofuel production requires improvements in both biomass
productivity and its energy density. Green microalgae store starch and oil as two major forms …

Centromere (CEN) identity is specified epigenetically by specialized nucleosomes
containing evolutionarily conserved CEN-specific histone H3 variant CENP-A (Cse4 in …

Kinetochores assemble on centromeres to drive chromosome segregation in eukaryotic
cells. Humans and budding yeast share most of the structural subunits of the kinetochore …