Many physiologic effects of l-glutamate, the major excitatory neurotransmitter in the
mammalian central nervous system, are mediated via signaling by ionotropic glutamate …

Anxiety disorders are the most prevalent psychiatric disorders and a leading cause of
disability. While there continues to be expansive research in posttraumatic stress disorder …

Psychiatry has always been characterized by a range of different models of and approaches
to mental disorder, which have sometimes brought progress in clinical practice, but have …

This narrative state-of-the-art review paper describes the progress in the understanding and
treatment of Posttraumatic Stress Disorder (PTSD). Over the last four decades, the scientific …

Obsessive-compulsive disorder (OCD) is a common, chronic, and oftentimes disabling
disorder. The only established first-line treatments for OCD are exposure and response …

This review is designed to systematically examine the available evidence about virtual
reality exposure therapy's (VRET) efficacy for phobias, critically describe some of the most …

Current medication for anxiety disorders is suboptimal in terms of efficiency and tolerability,
highlighting the need for improved drug treatments. In this review an overview of drugs …

Anxiety disorders are the most common mental disorders and are often chronic and
disabling. Although exposure-based treatments are effective, a substantial number of …

Anxiety disorders are among the most prevalent mental disorders, but the subcategory of
specific phobias has not been well studied. Phobias involve both fear and avoidance. For …

Background Virtual reality exposure therapy (VRET) for PTSD is an emerging treatment of
remarkable promise, but its efficacy and safety are still unclear. Our aim was to investigate …