Bacterial anti-microbial peptides and nano-sized drug delivery systems: The state of the art toward improved bacteriocins

A Radaic, MB de Jesus, YL Kapila - Journal of Controlled Release, 2020 - Elsevier
Antimicrobial peptides (AMP) are molecules consisting of 12–100 amino acids synthesized
by certain microbes and released extracellularly to inhibit the growth of other microbes …

The Role of P53 in Nanoparticle-Based Therapy for Cancer

O Szewczyk-Roszczenko, NA Barlev - Cells, 2023 - mdpi.com
p53 is arguably one of the most important tumor suppressor genes in humans. Due to the
paramount importance of p53 in the onset of cell cycle arrest and apoptosis, the p53 gene is …

Centyrin ligands for extrahepatic delivery of siRNA

D Klein, S Goldberg, CS Theile, R Dambra, K Haskell… - Molecular Therapy, 2021 - cell.com
RNA interference (RNAi) offers the potential to treat disease at the earliest onset by
selectively turning off the expression of target genes, such as intracellular oncogenes that …

Recuperating biopharmaceutical aspects of amphotericin B and paromomycin using a chitosan functionalized nanocarrier via oral route for enhanced anti-leishmanial …

S Parvez, G Yadagiri, A Karole, OP Singh… - Frontiers in cellular …, 2020 - frontiersin.org
The design and development of new pharmaceutical formulations for the existing anti-
leishmanial is a new strategic alternate to improve efficacy and safety rather than new drug …

Cationic solid lipid nanoparticles (SLN) complexed with plasmid DNA enhance prostate cancer cells (PC-3) migration

F Garcia-Fossa, MB de Jesus - Nanotoxicology, 2024 - Taylor & Francis
Nanotechnology applications in biomedicine have increased in recent decades, primarily as
therapeutic agents, drugs, and gene delivery systems. Among the nanoparticles used in …

Solid lipid nanoparticles loaded with Nisin (SLN-Nisin) are more effective than free Nisin as antimicrobial, Antibiofilm, and anticancer agents

A Radaic, E Malone, P Kamarajan… - Journal of biomedical …, 2022 - ingentaconnect.com
Bacteriocins are peptides produced by bacteria to inhibit the growth of other prokaryotes.
Nisin is a bacteriocin widely used in the food industry and for biomedical applications …

Mechanisms of solid lipid nanoparticles-triggered signaling pathways in eukaryotic cells

T Moraes-Lacerda, MB de Jesus - Colloids and Surfaces B: Biointerfaces, 2022 - Elsevier
Solid lipid nanoparticles (SLN) are used in various fields such as pharmaceutical, cosmetic,
and biomedical research and show promising results in delivering biomolecules. SLN …

Multi-dose intravenous administration of neutral and cationic liposomes in mice: an extensive toxicity study

S Andrade, JA Loureiro, S Ramirez, CSG Catumbela… - Pharmaceuticals, 2022 - mdpi.com
Liposomes are widely used as delivery systems for therapeutic purposes. However, the
toxicity associated with the multi-dose administration of these nanoparticles is not fully …

Solid lipid nanoparticles (slns): Advancements in modification strategies toward drug delivery vehicle

GMH Al-Sayadi, A Verma, Y Choudhary… - Pharmaceutical …, 2023 - ingentaconnect.com
Solid lipid nanoparticles are at the cornerstone of the swiftly growing area of medical
nanotechnology, having several potential functions in drug delivery, research, clinical care …

The state of the art of nanopsychiatry for schizophrenia diagnostics and treatment

A Radaic, D Martins-de-Souza - Nanomedicine: Nanotechnology, Biology …, 2020 - Elsevier
Schizophrenia is one of the top 25 causes of global diseases burdens in terms of years lived
with the disease and the emotional and economical strains it imposes on the society …