Migraine (Primer)

MD Ferrari, PJ Goadsby, B Rami… - Nature Reviews …, 2022 - search.proquest.com
Migraine is a common, chronic, disorder that is typically characterized by recurrent disabling
attacks of headache and accompanying symptoms, including aura. The aetiology is …

Sporadic and familial hemiplegic migraine: pathophysiological mechanisms, clinical characteristics, diagnosis, and management

MB Russell, A Ducros - The Lancet Neurology, 2011 - thelancet.com
Hemiplegic migraine is a rare form of migraine with aura that involves motor aura
(weakness). This type of migraine can occur as a sporadic or a familial disorder. Familial …

Mutation in the neuronal voltage-gated sodium channel SCN1A in familial hemiplegic migraine

M Dichgans, T Freilinger, G Eckstein, E Babini… - The Lancet, 2005 - thelancet.com
Background Familial hemiplegic migraine is an autosomal dominant severe subtype of
migraine with aura characterised by some degree of hemiparesis during the attacks. So far …

De novo mutations in ATP1A3 cause alternating hemiplegia of childhood

EL Heinzen, KJ Swoboda, Y Hitomi, F Gurrieri… - Nature …, 2012 - nature.com
Alternating hemiplegia of childhood (AHC) is a rare, severe neurodevelopmental syndrome
characterized by recurrent hemiplegic episodes and distinct neurological manifestations …

A Cacna1a knockin migraine mouse model with increased susceptibility to cortical spreading depression

AMJM van den Maagdenberg, D Pietrobon… - Neuron, 2004 - cell.com
Migraine is a common, disabling, multifactorial, episodic neurovascular disorder of unknown
etiology. Familial hemiplegic migraine type 1 (FHM-1) is a Mendelian subtype of migraine …

Activated astrocytes attenuate neocortical seizures in rodent models through driving Na+-K+-ATPase

J Zhao, J Sun, Y Zheng, Y Zheng, Y Shao, Y Li… - Nature …, 2022 - nature.com
Epileptic seizures are widely regarded to occur as a result of the excitation-inhibition
imbalance from a neuro-centric view. Although astrocyte-neuron interactions are …

Recent advances in luminescent heavy metal complexes for sensing

DL Ma, VPY Ma, DSH Chan, KH Leung, HZ He… - Coordination Chemistry …, 2012 - Elsevier
Luminescent metal complexes have attracted increasing attention in the literature over the
last few decades. In particular, transition metal compounds have been widely studied for …

Mutations in the Na+/K+-ATPase α3 gene ATP1A3 are associated with rapid-onset dystonia parkinsonism

P de Carvalho Aguiar, KJ Sweadner, JT Penniston… - Neuron, 2004 - cell.com
Rapid-onset dystonia-parkinsonism (RDP, DYT12) is a distinctive autosomal-dominant
movement disorder with variable expressivity and reduced penetrance characterized by …

FXYD proteins: new regulators of Na-K-ATPase

K Geering - American Journal of Physiology-Renal …, 2006 - journals.physiology.org
FXYD proteins belong to a family of small-membrane proteins. Recent experimental
evidence suggests that at least five of the seven members of this family, FXYD1 …

Hyperexcitable interneurons trigger cortical spreading depression in an Scn1a migraine model

E Auffenberg, UBS Hedrich, R Barbieri… - The Journal of …, 2021 - Am Soc Clin Investig
Cortical spreading depression (CSD), a wave of depolarization followed by depression of
cortical activity, is a pathophysiological process implicated in migraine with aura and various …