The cancer transcriptome is remarkably complex, including low-abundance transcripts,
many not polyadenylated. To fully characterize the transcriptome of localized prostate …

Prostate cancer is the second most common male cancer affecting Western society. Despite
substantial advances in the exploration of prostate cancer biomarkers and treatment …

Accumulating evidence suggests that prostatic cancers represent a group of histologically
and molecularly heterogeneous diseases with variable clinical courses. In accordance with …

Gene fusions that contribute to oncogenicity can be explored for identifying cancer
biomarkers and potential drug targets. To investigate the nature and distribution of fusion …

The review initially provides a short introduction to prostate cancer (PCa) incidence,
mortality, and diagnostics. Next, the need for novel biomarkers for PCa diagnostics is briefly …

The awareness of genome complexity brought a radical approach to the study of
transcriptome, opening eyes to single RNAs generated from two or more adjacent genes …

Abstract Background Prostate cancer (PCa) is one of the most prevalent cancers worldwide.
The clinical manifestations and molecular characteristics of PCa are highly variable …

Fusion genes have been implicated in the development and progression of several types of
sarcomas, serving as valuable diagnostic and prognostic markers, as well as potential …

Breast cancer is the most common neoplasm among females. Estrogen receptor (ESR)
signaling has a prominent impact in the pathogenesis of breast cancer. Among the …

Transcripts originating from the transcriptional read through of two adjacent, similarly
oriented genes have been identified in normal and neoplastic tissues, but their functional …