Mechanical forces direct stem cell behaviour in development and regeneration
Stem cells and their local microenvironment, or niche, communicate through mechanical
cues to regulate cell fate and cell behaviour and to guide developmental processes. During …
cues to regulate cell fate and cell behaviour and to guide developmental processes. During …
Biointerface design for vertical nanoprobes
R Elnathan, MG Barbato, X Guo, A Mariano… - Nature Reviews …, 2022 - nature.com
Biointerfaces mediate safe and efficient cell manipulation, which is essential for biomedical
innovations in advanced therapies and diagnostics. The biointerface established by vertical …
innovations in advanced therapies and diagnostics. The biointerface established by vertical …
Functional and biomimetic materials for engineering of the three-dimensional cell microenvironment
The cell microenvironment has emerged as a key determinant of cell behavior and function
in development, physiology, and pathophysiology. The extracellular matrix (ECM) within the …
in development, physiology, and pathophysiology. The extracellular matrix (ECM) within the …
[HTML][HTML] The influence of nanotopography on cell behaviour through interactions with the extracellular matrix–A review
Nanotopography presents an effective physical approach for biomaterial cell manipulation
mediated through material-extracellular matrix interactions. The extracellular matrix that …
mediated through material-extracellular matrix interactions. The extracellular matrix that …
Bone physiology as inspiration for tissue regenerative therapies
D Lopes, C Martins-Cruz, MB Oliveira, JF Mano - Biomaterials, 2018 - Elsevier
The development, maintenance of healthy bone and regeneration of injured tissue in the
human body comprise a set of intricate and finely coordinated processes. However, an …
human body comprise a set of intricate and finely coordinated processes. However, an …
Static and dynamic: evolving biomaterial mechanical properties to control cellular mechanotransduction
The extracellular matrix (ECM) is a highly dynamic system that constantly offers physical,
biological, and chemical signals to embraced cells. Increasing evidence suggests that …
biological, and chemical signals to embraced cells. Increasing evidence suggests that …
Bioengineering strategies to accelerate stem cell therapeutics
CM Madl, SC Heilshorn, HM Blau - Nature, 2018 - nature.com
Although only a few stem cell-based therapies are currently available to patients, stem cells
hold tremendous regenerative potential, and several exciting clinical applications are on the …
hold tremendous regenerative potential, and several exciting clinical applications are on the …
The horizon of materiobiology: a perspective on material-guided cell behaviors and tissue engineering
Although the biological functions of cell and tissue can be regulated by biochemical factors
(eg, growth factors, hormones), the biophysical effects of materials on the regulation of …
(eg, growth factors, hormones), the biophysical effects of materials on the regulation of …
Functional graphene nanomaterials based architectures: biointeractions, fabrications, and emerging biological applications
Functional graphene nanomaterials (FGNs) are fast emerging materials with extremely
unique physical and chemical properties and physiological ability to interfere and/or interact …
unique physical and chemical properties and physiological ability to interfere and/or interact …
Mechanical memory and dosing influence stem cell fate
We investigated whether stem cells remember past physical signals and whether these can
be exploited to dose cells mechanically. We found that the activation of the Yes-associated …
be exploited to dose cells mechanically. We found that the activation of the Yes-associated …