Stem cells and their local microenvironment, or niche, communicate through mechanical
cues to regulate cell fate and cell behaviour and to guide developmental processes. During …

Biointerfaces mediate safe and efficient cell manipulation, which is essential for biomedical
innovations in advanced therapies and diagnostics. The biointerface established by vertical …

The cell microenvironment has emerged as a key determinant of cell behavior and function
in development, physiology, and pathophysiology. The extracellular matrix (ECM) within the …

Nanotopography presents an effective physical approach for biomaterial cell manipulation
mediated through material-extracellular matrix interactions. The extracellular matrix that …

The development, maintenance of healthy bone and regeneration of injured tissue in the
human body comprise a set of intricate and finely coordinated processes. However, an …

The extracellular matrix (ECM) is a highly dynamic system that constantly offers physical,
biological, and chemical signals to embraced cells. Increasing evidence suggests that …

Although only a few stem cell-based therapies are currently available to patients, stem cells
hold tremendous regenerative potential, and several exciting clinical applications are on the …

Although the biological functions of cell and tissue can be regulated by biochemical factors
(eg, growth factors, hormones), the biophysical effects of materials on the regulation of …

Functional graphene nanomaterials (FGNs) are fast emerging materials with extremely
unique physical and chemical properties and physiological ability to interfere and/or interact …

We investigated whether stem cells remember past physical signals and whether these can
be exploited to dose cells mechanically. We found that the activation of the Yes-associated …