Most vertebrates are infected with one or more herpesviruses and remain so for the rest of
their lives. The relationship of immunocompetent healthy host with herpesviruses may …

The B-cell receptor (BCR) for antigen is a key sensor required for B-cell development,
survival, and activation. Rigorous selection checkpoints ensure that the mature B-cell …

The association of autoimmune diseases with particular allellic products of the class-II major
histocompatibility complex (MHCII) region implicates the presentation of the offending self …

A monoclonal antibody against the C-type lectin DEC205 (αDEC205) is an effective vehicle
for delivery of antigens to dendritic cells through creation of covalent αDEC205–antigen …

We have generated, via somatic cell nuclear transfer, two independent lines of transnuclear
mice, using as nuclear donors CD8 T cells, sorted by tetramer staining, that recognize the …

Age-related alterations of the immune system compromise the host's ability to respond to
pathogens, but how immune aging is regulated is still poorly understood. Here, we identify …

Influenza A virus-specific B lymphocytes and the antibodies they produce protect against
infection. However, the outcome of interactions between an influenza haemagglutinin …

We investigated the influence of a transient treatment of corticosteroid on CD8+ T cells
during herpesvirus infection. Dexamethasone, a synthetic corticosteroid, induced apoptosis …

To gain insights into the molecular mechanisms and pathways involved in the activation of γ-
herpesvirus (MHV68)-specific T cell receptor transnuclear (TN) CD8+ T cells, we performed …

Galectins play diverse roles in pathophysiology of infectious diseases and cancers. Galectin-
3 is one of the most studied family member and the only chimeric type lectin. Many aspects …