Temporary immersion systems (TISs): a comprehensive review

AH Mirzabe, A Hajiahmad, A Fadavi, S Rafiee - Journal of Biotechnology, 2022 - Elsevier
The temporary immersion systems (TISs) have been widely used in plant biotechnology.
TISs have different advantages from the point of micropropagation and production of …

Bioreactor technologies for enhanced organoid culture

JP Licata, KH Schwab, YE Har-El… - International Journal of …, 2023 - mdpi.com
An organoid is a 3D organization of cells that can recapitulate some of the structure and
function of native tissue. Recent work has seen organoids gain prominence as a valuable …

Growing tissues in real and simulated microgravity: new methods for tissue engineering

D Grimm, M Wehland, J Pietsch… - … Engineering Part B …, 2014 - liebertpub.com
Tissue engineering in simulated (s-) and real microgravity (r-μ g) is currently a topic in Space
medicine contributing to biomedical sciences and their applications on Earth. The principal …

The impact of simulated and real microgravity on bone cells and mesenchymal stem cells

C Ulbrich, M Wehland, J Pietsch… - BioMed research …, 2014 - Wiley Online Library
How microgravity affects the biology of human cells and the formation of 3D cell cultures in
real and simulated microgravity (r‐and s‐µg) is currently a hot topic in biomedicine. In r‐and …

Biomanufacturing of 3D tissue constructs in microgravity and their applications in human pathophysiological studies

Z Ren, AD Harriot, DB Mair, MK Chung… - Advanced …, 2023 - Wiley Online Library
The growing interest in bioengineering in‐vivo‐like 3D functional tissues has led to novel
approaches to the biomanufacturing process as well as expanded applications for these …

From “bench to bedside”: current advancement on large-scale production of mesenchymal stem cells

V Bunpetch, H Wu, S Zhang… - Stem cells and …, 2017 - liebertpub.com
Mesenchymal stem cells (MSCs) are the primary cell source in cell therapy and regenerative
medicine due to its extraordinary self-renewing capacity and multilineage differentiation …

[HTML][HTML] Computational fluid dynamics modeling of cell cultures in bioreactors and its potential for cultivated meat production—A mini-review

FJC Rivera, J Chen - Future Foods, 2022 - Elsevier
Cultivated meat production was developed as a response to the rapidly increasing demand
for meat consumption. Bioreactor designs were adapted from other bioprocesses to account …

Regulation of mesenchymal stem cell 3D microenvironment: From macro to microfluidic bioreactors

S Sart, SN Agathos, Y Li, T Ma - Biotechnology journal, 2016 - Wiley Online Library
Human mesenchymal stem cells (hMSCs) have emerged as an important cell type in cell
therapy and tissue engineering. In these applications, maintaining the therapeutic properties …

Application of CFD in Bioprocessing: Separation of mammalian cells using disc stack centrifuge during production of biotherapeutics

LK Shekhawat, J Sarkar, R Gupta, S Hadpe… - Journal of …, 2018 - Elsevier
Centrifugation continues to be one of the most commonly used unit operations for achieving
efficient harvest of the product from the mammalian cell culture broth during production of …

Applications of computer modeling and simulation in cartilage tissue engineering

D Pearce, S Fischer, F Huda, A Vahdati - Tissue engineering and …, 2020 - Springer
Background: Advances in cartilage tissue engineering have demonstrated noteworthy
potential for developing cartilage for implantation onto sites impacted by joint degeneration …