Signal processing in complex chemotaxis pathways

SL Porter, GH Wadhams, JP Armitage - Nature Reviews Microbiology, 2011 - nature.com
Bacteria use chemotaxis to migrate towards environments that are better for growth.
Chemoreceptors detect changes in attractant levels and signal through two-component …

Spatial organization in bacterial chemotaxis

V Sourjik, JP Armitage - The EMBO journal, 2010 - embopress.org
Spatial organization of signalling is not an exclusive property of eukaryotic cells. Despite the
fact that bacterial signalling pathways are generally simpler than those in eukaryotes, there …

A modular gradient‐sensing network for chemotaxis in Escherichia coli revealed by responses to time‐varying stimuli

TS Shimizu, Y Tu, HC Berg - Molecular systems biology, 2010 - embopress.org
The Escherichia coli chemotaxis‐signaling pathway computes time derivatives of
chemoeffector concentrations. This network features modules for signal …

Response rescaling in bacterial chemotaxis

MD Lazova, T Ahmed, D Bellomo… - Proceedings of the …, 2011 - National Acad Sciences
Sensory systems rescale their response sensitivity upon adaptation according to simple
strategies that recur in processes as diverse as single-cell signaling, neural network …

Core unit of chemotaxis signaling complexes

M Li, GL Hazelbauer - … of the National Academy of Sciences, 2011 - National Acad Sciences
Bacterial chemoreceptors, histidine kinase CheA, and coupling protein CheW form clusters
of chemotaxis signaling complexes. In signaling complexes kinase activity is enhanced …

Bacterial chemoreceptors: providing enhanced features to two-component signaling

GL Hazelbauer, WC Lai - Current opinion in microbiology, 2010 - Elsevier
Bacteria perform chemotaxis utilizing core two-component signaling systems to which have
been added enhanced features of signal amplification, sensory adaptation, molecular …

The source of high signal cooperativity in bacterial chemosensory arrays

GE Piñas, V Frank, A Vaknin… - Proceedings of the …, 2016 - National Acad Sciences
The Escherichia coli chemosensory system consists of large arrays of transmembrane
chemoreceptors associated with a dedicated histidine kinase, CheA, and a linker protein …

Information processing in bacteria: memory, computation, and statistical physics: a key issues review

G Lan, Y Tu - Reports on Progress in Physics, 2016 - iopscience.iop.org
Living systems have to constantly sense their external environment and adjust their internal
state in order to survive and reproduce. Biological systems, from as complex as the brain to …

Responses of Escherichia coli Bacteria to Two Opposing Chemoattractant Gradients Depend on the Chemoreceptor Ratio

Y Kalinin, S Neumann, V Sourjik, M Wu - Journal of bacteriology, 2010 - Am Soc Microbiol
Escherichia coli chemotaxis has long served as a simple model of environmental signal
processing, and bacterial responses to single chemical gradients are relatively well …

Mechanism of bidirectional thermotaxis in Escherichia coli

A Paulick, V Jakovljevic, SM Zhang, M Erickstad… - Elife, 2017 - elifesciences.org
In bacteria various tactic responses are mediated by the same cellular pathway, but sensing
of physical stimuli remains poorly understood. Here, we combine an in-vivo analysis of the …