Pharmacotherapeutic potential of ginger and its compounds in age-related neurological disorders

JG Choi, SY Kim, M Jeong, MS Oh - Pharmacology & therapeutics, 2018 - Elsevier
Age-related neurological disorders (ANDs), including neurodegenerative diseases, are
multifactorial disorders with a risk that increases with aging. ANDs are generally …

A critical view on the analysis of fluorescence quenching data for determining ligand–protein binding affinity

KA Bakar, SR Feroz - Spectrochimica Acta Part A: Molecular and …, 2019 - Elsevier
The past decade has seen an increase in the number of research papers on ligand binding
to proteins based on fluorescence spectroscopy. In most cases, determination of the binding …

[HTML][HTML] Binding of an anticancer drug, axitinib to human serum albumin: Fluorescence quenching and molecular docking study

S Tayyab, MM Izzudin, MZ Kabir, SR Feroz… - … of Photochemistry and …, 2016 - Elsevier
Binding characteristics of a promising anticancer drug, axitinib (AXT) to human serum
albumin (HSA), the major transport protein in human blood circulation, were studied using …

Molecular interaction study of an anticancer drug, ponatinib with human serum albumin using spectroscopic and molecular docking methods

S Tayyab, SE Sam, MZ Kabir, NFW Ridzwan… - … Acta Part A: Molecular …, 2019 - Elsevier
Binding of a potent anticancer agent, ponatinib (PTB) to human serum albumin (HSA), main
ligand transporter in blood plasma was analyzed with several spectral techniques such as …

Decoding the intermolecular recognition mode of a potent anticancer drug, abiraterone with human serum albumin: Assessments through spectroscopic and …

MZ Kabir, J Seng, SB Mohamad, B Uslu - Journal of Molecular Structure, 2024 - Elsevier
Abiraterone (ABR) is an FDA-approved anticancer drug that possesses repressing
properties against the progression of advanced prostate cancer. The combination of …

Elucidating the binding propensity of naphthyl hydroxamic acid to human serum albumin (HSA): multi-spectroscopic and molecular modeling approach

R Agrawal, Y Thakur, M Tripathi, MK Siddiqi… - Journal of Molecular …, 2019 - Elsevier
The association of human serum albumin (HSA) and its interaction with drug and other novel
compound has garnered keen interest in designing and development for new compounds …

Shedding light on the molecular interaction between the Hepatitis B virus inhibitor, clevudine, and human serum albumin: Thermodynamic, spectroscopic, microscopic …

M Abubakar, S Kandandapani, SB Mohamed… - Journal of Molecular …, 2022 - Elsevier
The molecular interaction between clevudine (CLV), a hepatitis B virus inhibitor, and human
serum albumin (HSA), the major transporter in plasma, was investigated via fluorescence …

Neuroprotective effects of Zingiber officinale against lead-induced toxicity in Wistar rats

AB Enogieru, O Momodu - Nutrire, 2022 - Springer
Purpose This study investigated the protective and antioxidative effect of aqueous root
extract of ginger (Zingiber officinale)(AREG) against lead (Pb)-induced neurotoxicity in adult …

[HTML][HTML] Characterization of the binding of an anticancer drug, lapatinib to human serum albumin

MZ Kabir, AK Mukarram, SB Mohamad, Z Alias… - … of Photochemistry and …, 2016 - Elsevier
Interaction of a promising anticancer drug, lapatinib (LAP) with the major transport protein in
human blood circulation, human serum albumin (HSA) was investigated using fluorescence …

Investigation on the binding of cyanobacterial metabolite calothrixin A with human serum albumin for evaluating its potential toxicology

X Liao, C Zhu, H Zhang, X Li, X Wen, SL Zhang… - Food and Chemical …, 2021 - Elsevier
Calothrixin A (CLA), as a carbazole-1, 4-quinone alkaloid with unique indolo [3, 2-j]
phenanthridine framework, is a natural metabolite from the Calothrix cyanobacteria. Since …