Biosynthesis and biotechnological production of statins by filamentous fungi and application of these cholesterol-lowering drugs

M Manzoni, M Rollini - Applied microbiology and biotechnology, 2002 - Springer
Hypercholesterolemia is considered an important risk factor in coronary artery disease. Thus
the possibility of controlling de novo synthesis of endogenous cholesterol, which is nearly …

Secondary metabolites of the fungusMonascus: A review

P Jůzlová, L Martinkova, V Křen - Journal of Industrial Microbiology, 1996 - Springer
This review deals with polyketides produced by the filamentous fungus Monascus which
include: 1) a group of yellow, orange and red pigments, 2) a group of …

Constituents of red yeast rice, a traditional Chinese food and medicine

J Ma, Y Li, Q Ye, J Li, Y Hua, D Ju… - Journal of agricultural …, 2000 - ACS Publications
Detailed analyses were undertaken of the natural constituents of red yeast rice, a traditional
Chinese medicine and food known for centuries to improve blood circulation. Preparation of …

[图书][B] Handbook of fermented functional foods

ERT Farnworth - 2008 - taylorfrancis.com
For centuries, people around the world have used fermentation to preserve and enhance the
flavor of a wide variety of foods. Today, complex interactions of microbiota in the digestive …

Characterization of monascidin A from Monascus as citrinin

PJ Blanc, JP Laussac, J Le Bars, P Le Bars… - International journal of …, 1995 - Elsevier
Following our investigations on red pigments and monascidin co-production by Monascus
species, the antibiotic called monascidin A was characterized as citrinin. Evidence was …

Biologically active components and nutraceuticals in the Monascus-fermented rice: a review

YL Lin, TH Wang, MH Lee, NW Su - Applied microbiology and …, 2008 - Springer
Monascus-fermented rice has traditionally been used as a natural food colorant and food
preservative of meat and fish for centuries. It has recently become a popular dietary …

Targeting the mevalonate cascade as a new therapeutic approach in heart disease, cancer and pulmonary disease

B Yeganeh, E Wiechec, SR Ande, P Sharma… - Pharmacology & …, 2014 - Elsevier
The cholesterol biosynthesis pathway, also known as the mevalonate (MVA) pathway, is an
essential cellular pathway that is involved in diverse cell functions. The enzyme 3-hydroxy-3 …

Identification and chemical profiling of monacolins in red yeast rice using high-performance liquid chromatography with photodiode array detector and mass …

Y Li, F Zhang, Z Wang, Z Hu - Journal of pharmaceutical and biomedical …, 2004 - Elsevier
Monascus purpureus-fermented rice (red yeast rice) was one of the food supplements that
had the ability of lowering the blood-lipid levels, and monacolins have been proved to be …

An analysis of nine proprietary Chinese red yeast rice dietary supplements: implications of variability in chemical profile and contents

D Heber, A Lembertas, QY Lu… - The Journal of …, 2001 - liebertpub.com
Objectives: Some strains of Chinese red yeast rice, when prepared by solid fermentation,
produce compounds called monacolins that inhibit cholesterol production. When used as a …

Natural products containing 'decalin'motif in microorganisms

G Li, S Kusari, M Spiteller - Natural Product Reports, 2014 - pubs.rsc.org
Covering: up to February 2014 Microorganisms are well-known producers of a wide variety
of bioactive compounds that are utilized not only for their primary metabolism but also for …