The epidemic of hepatitis C virus (HCV) infection in Europe is continuously evolving and
epidemiological parameters (prevalence, incidence, disease transmission patterns and …

Hepatitis C virus (HCV) is a leading cause of chronic blood-borne infection and chronic liver
disease. The global epidemic of HCV infection emerged in the second half of the 20th …

The transfusion of red cell concentrates (RCC) is indicated in order to achieve a fast
increase in the supply of oxygen to the tissues, when the concentration of haemoglobin (Hb) …

Infections are major complications and constitute the second most common cause of
mortality and a main cause of morbidity in patients with thalassaemia, a group of genetic …

Hepatocellular carcinoma (HCC) frequently complicates hepatic cirrhosis secondary to viral
infection or iron overload. Therefore, patients affected by thalassaemia syndromes have a …

Before the introduction of hepatitis C virus (HCV) screening for blood donors, the risk of
acquiring HCV infection as a result of a transfusion was about 10%. The aim of this study …

The β thalassemia syndromes constitute the most frequent inherited anemia managed with
chronic red cell transfusions around the world. 1, 2 The prevalence of thalassemia in the …

One of transfusion's side effects is alloimmunization against red blood cell (RBC) antigens.
Early diagnosis by antibody screening is an important step in the detection of these …

The incidence of hepatocellular carcinoma (HCC) in patients with thalassemia is on the rise.
The 2 well recognized HCC risk factors in thalassemia are iron overload and chronic viral …

The role of iron overload as cause of liver dysfunction has never been studied in detail in
patients without concomitant hepatotropic infections who receive multiple transfusions. We …