Chemistry of MRI contrast agents: current challenges and new frontiers
Tens of millions of contrast-enhanced magnetic resonance imaging (MRI) exams are
performed annually around the world. The contrast agents, which improve diagnostic …
performed annually around the world. The contrast agents, which improve diagnostic …
The use of the macrocyclic chelator DOTA in radiochemical separations
Radiometals play an important role in the diagnosis of physiological processes in vivo by
means of imaging technologies, but also increasingly contribute to the treatment of diseases …
means of imaging technologies, but also increasingly contribute to the treatment of diseases …
Metal-involved theranostics: An emerging strategy for fighting Alzheimer's disease
Alzheimer's disease (AD) is the most prevalent illness among the neurodegenerative
disorders that are progressive, irreversible and incurable so far. Although the etiological …
disorders that are progressive, irreversible and incurable so far. Although the etiological …
Amyloid β-targeted metal complexes for potential applications in Alzheimer's disease
H Liu, Y Qu, X Wang - Future medicinal chemistry, 2018 - Taylor & Francis
Alzheimer's disease (AD) is currently an incurable neurodegenerative disorder that affects
millions of people around the world. The aggregation of amyloid-β peptides (Aβ), one of the …
millions of people around the world. The aggregation of amyloid-β peptides (Aβ), one of the …
Magnetic nanoparticles applications for amyloidosis study and detection: a review
J Pansieri, M Gerstenmayer, F Lux, S Mériaux… - Nanomaterials, 2018 - mdpi.com
Magnetic nanoparticles (MNPs) have great potential in biomedical and clinical applications
because of their many unique properties. This contribution provides an overview of the …
because of their many unique properties. This contribution provides an overview of the …
Development of a 213Bi-Labeled Pyridyl Benzofuran for Targeted α-Therapy of Amyloid-β Aggregates
AA Bender, EK Kirkeby, DJ Cross… - Journal of Nuclear …, 2024 - jnm.snmjournals.org
Alzheimer disease is a neurodegenerative disorder with limited treatment options. It is
characterized by the presence of several biomarkers, including amyloid-β aggregates, which …
characterized by the presence of several biomarkers, including amyloid-β aggregates, which …
Lanthanide complexes in molecular magnetic resonance imaging and theranostics
Lanthanide complexes have attracted much attention in the biomedical field, and today
various imaging applications make use of their versatile magnetic and luminescence …
various imaging applications make use of their versatile magnetic and luminescence …
Efficient characterization of multiple binding sites of small molecule imaging ligands on amyloid-beta, tau and alpha-synuclein
J Sobek, J Li, BF Combes, JA Gerez… - European journal of …, 2024 - Springer
Purpose There is an unmet need for compounds to detect fibrillar forms of alpha-synuclein
(αSyn) and 4-repeat tau, which are critical in many neurodegenerative diseases. Here, we …
(αSyn) and 4-repeat tau, which are critical in many neurodegenerative diseases. Here, we …
Alzheimer's disease: The use of contrast agents for magnetic resonance imaging to detect amyloid beta peptide inside the brain
M Salerno, DSD Porqueras - Coordination Chemistry Reviews, 2016 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative disease that causes progressive and
irreversible loss of mental functions. There is no cure for the disease, which worsens as it …
irreversible loss of mental functions. There is no cure for the disease, which worsens as it …
Lanthanide conjugates as versatile instruments for therapy and diagnostics
C Herlan, S Bräse - Dalton Transactions, 2020 - pubs.rsc.org
Lanthanides have demonstrated outstanding properties in many fields of research including
biology and medicinal chemistry. Their unique luminescence and magnetic properties make …
biology and medicinal chemistry. Their unique luminescence and magnetic properties make …