Approaches for enhancing oral bioavailability of peptides and proteins

J Renukuntla, AD Vadlapudi, A Patel… - International journal of …, 2013 - Elsevier
Oral delivery of peptide and protein drugs faces immense challenge partially due to the
gastrointestinal (GI) environment. In spite of considerable efforts by industrial and academic …

The potential of chitosan in nanomedicine: An overview of the cytotoxicity of chitosan based nanoparticles

J Frigaard, JL Jensen, HK Galtung… - Frontiers in …, 2022 - frontiersin.org
The unique properties and applications of nanotechnology in targeting drug delivery,
cosmetics, fabrics, water treatment and food packaging have received increased focus the …

Advanced materials for drug delivery across mucosal barriers

SP Bandi, S Bhatnagar, VVK Venuganti - Acta biomaterialia, 2021 - Elsevier
Mucus is a viscoelastic gel that traps pathogens and other foreign particles to limit their
penetration into the underlying epithelium. Dosage forms containing particle-based drug …

Thiolated chitosans: A multi-talented class of polymers for various applications

C Federer, M Kurpiers… - Biomacromolecules, 2020 - ACS Publications
Various properties of chitosan can be customized by thiolation for very specific needs in a
wide range of application areas. Since the discovery of thiolated chitosans, many studies …

Oral insulin delivery: how far are we?

P Fonte, F Araújo, S Reis… - Journal of diabetes …, 2013 - journals.sagepub.com
Oral delivery of insulin may significantly improve the quality of life of diabetes patients who
routinely receive insulin by the subcutaneous route. In fact, compared with this …

Chitosan and its derivatives as vehicles for drug delivery

G Huang, Y Liu, L Chen - Drug delivery, 2017 - Taylor & Francis
Chitosan and its derivatives as vehicles for drug delivery can achieve the purpose of
sustained release and controlled release for drugs, improve the stability of drugs, and …

A new horizon in modifications of chitosan: syntheses and applications

A Jain, A Gulbake, S Shilpi, A Jain… - Critical Reviews™ in …, 2013 - dl.begellhouse.com
Chitosan is a naturally occurring biopolymer having diversified applications not only in the
pharmaceutical field, but also in the biomedical profession. The presence of functional …

Design and application of chitosan microspheres as oral and nasal vaccine carriers: an updated review

MA Islam, J Firdous, YJ Choi, CH Yun… - International journal of …, 2012 - Taylor & Francis
Chitosan, a natural biodegradable polymer, is of great interest in biomedical research due to
its excellent properties including bioavailability, nontoxicity, high charge density, and …

Oral drug delivery research in Europe

RJ Mrsny - Journal of controlled release, 2012 - Elsevier
The oral delivery of drugs is considered by decision-makers in the pharmaceutical industry
to be the most appealing route of administration. This belief has led to the identification of …

Mucoadhesive chitosan derivatives as novel drug carriers

M Ariful Islam, TE Park, E Reesor… - Current …, 2015 - ingentaconnect.com
Chitosan on its own is a well-established natural polymer and is widely regarded as a
biodegradable, biocompatible and nontoxic material for drug delivery applications. Although …