Dengue is the leading mosquito-borne viral illness infecting humans. Owing to the
circulation of multiple serotypes, global expansion of the disease and recent gains in …

DENV is a major public health problem worldwide, thus underlining the overall significance
of the proposed Program. The four dengue virus (DENV) serotypes (1–4) cause the most …

T-cell immunity is likely to play a role in protection against SARS-CoV-2 by helping generate
neutralizing antibodies. We longitudinally studied CD4 T-cell responses to the M, N, and S …

In late 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) triggered the
global coronavirus disease 2019 (COVID-19) pandemic. Although most infections cause a …

There is a great need for the development of vaccines that induce potent and long-lasting
protective immunity against SARS-CoV-2. Multimeric display of the antigen combined with …

How innate and adaptive immune responses work in concert to resolve influenza disease is
yet to be fully investigated in one single study. Here, we utilize longitudinal samples from …

The dynamics of host-virus interactions, and impairment of the host's immune surveillance
by dengue virus (DENV) serotypes largely remain ambiguous. Several experimental and …

Dengue is one of the most frequently transmitted mosquito-borne diseases in the world,
which creates a significant public health concern globally, especially in tropical and …

Dengue virus (DENV) is a member of the Flavivirus family that includes Zika virus (ZIKV),
West Nile virus, Japanese encephalitis virus, and yellow fever virus. As the most prevalent of …

Arboviral infections such as Chikungunya (CHIKV), Dengue (DENV) and Zika (ZIKV) are a
major disease burden in tropical and sub-tropical countries, and there are no effective …