Carrying excess body fat is a leading cause of cancer. Epidemiologic evidence gives strong
clues about the mechanisms that link excess adiposity to risk for several cancer sites. For …

Determination of the role of insulin-like growth factor (IGF) family components in
carcinogenesis of several human tumors is based on numerous epidemiological and pre …

Background: Cancer is the second leading cause of death in the United States. Dietary
factors account for at least 30% of all cancers in Western countries. As people do not …

Platinum plays a central role in the therapy of ovarian cancer, and the emergence of
platinum resistance is a major obstacle for clinical management of the disease. We treated …

Background Metastatic recurrence of ovarian cancer is the foremost cause of postoperative
mortality. With recent research indicating that inhalation of anaesthetics may influence …

Insulin-like growth factor 1 (IGF1) is produced by ovarian cancer cells and it has been
suggested that it plays an important role in tumor progression. In this study, we report that …

Objective The purpose of this article is to review the association of the obesity pandemic with
appearance of cancers in young adults under age 50 and to define potential mechanisms by …

The insulin-like growth factor (IGF) system comprises multiple growth factor receptors,
including insulin-like growth factor 1 receptor (IGF-1R), insulin receptor (IR)-A and-B. These …

The majority of ovarian cancer patients acquire resistance to standard platinum
chemotherapy and novel therapies to reduce tumor burden and ascites accumulation are …

Lin-28 and lin-28B are RNA-binding proteins which can block microRNA let-7 maturation
and affect the differentiation and proliferation of embryonic stem cells. Lin-28 may also …