The renin-angiotensin-aldosterone system (RAAS) signaling pathways and cancer: foes versus allies
The renin-angiotensin-aldosterone system (RAAS), is an old system with new fundamental
roles in cancer biology which influences cell growth, migration, death, and metastasis. RAAS …
roles in cancer biology which influences cell growth, migration, death, and metastasis. RAAS …
Interactions of the renin-angiotensin system in colorectal cancer and metastasis
WK Childers - International Journal of Colorectal Disease, 2015 - Springer
The novel function of the renin-angiotensin system (RAS) is cardiovascular homeostasis.
While the major active mediator angiotensin II (ANG II) produces most of the physiologic …
While the major active mediator angiotensin II (ANG II) produces most of the physiologic …
Histomorphometry changes and decreased reactivity to angiotensin II in the ileum and colon of streptozotocin-induced diabetic rats
M Esteves-Monteiro, D Menezes-Pinto… - International Journal of …, 2022 - mdpi.com
Diabetes mellitus (DM) is a chronic progressive metabolic disorder associated with several
gastrointestinal complications, affecting up to 75% of patients. Knowing that Angiotensin II …
gastrointestinal complications, affecting up to 75% of patients. Knowing that Angiotensin II …
Interaction between the renin–angiotensin system and enteric neurotransmission contributes to colonic dysmotility in the TNBS-induced model of colitis
M Ferreira-Duarte, T Rodrigues-Pinto, T Sousa… - International Journal of …, 2021 - mdpi.com
Angiotensin II (Ang II) regulates colon contraction, acting not only directly on smooth muscle
but also indirectly, interfering with myenteric neuromodulation mediated by the activation of …
but also indirectly, interfering with myenteric neuromodulation mediated by the activation of …
Systematic-Narrative Hybrid Literature Review: Crosstalk between Gastrointestinal Renin–Angiotensin and Dopaminergic Systems in the Regulation of Intestinal …
In the first part of this article, the role of intestinal epithelial tight junctions (TJs), together with
gastrointestinal dopaminergic and renin–angiotensin systems, are narratively reviewed to …
gastrointestinal dopaminergic and renin–angiotensin systems, are narratively reviewed to …
Angiotensin II type II receptors and colonic dysmotility in 2, 4‐dinitrofluorobenzenesulfonic acid‐induced colitis in rats
MG Zizzo, M Auteri, A Amato, G Caldara… - …, 2017 - Wiley Online Library
Abstract Background Angiotensin II (Ang II), the main peptide of the renin‐angiotensin
system (RAS), has been suggested to be involved in inflammatory bowel diseases. Since …
system (RAS), has been suggested to be involved in inflammatory bowel diseases. Since …
PD123319, angiotensin II type II receptor antagonist, inhibits oxidative stress and inflammation in 2, 4-dinitrobenzene sulfonic acid-induced colitis in rat and …
Angiotensin II, the main effector of renin angiotensin system, plays an important role in the
inflammatory process and most of its effects are mediated through the AT1 receptor …
inflammatory process and most of its effects are mediated through the AT1 receptor …
Opposite effects of dopamine on the mechanical activity of circular and longitudinal muscle of human colon
MG Zizzo, A Bellanca, A Amato… - Neurogastroenterology & …, 2020 - Wiley Online Library
Background Because dopamine (DA) has gained increasing evidence as modulator of gut
motility, we aimed to characterize dopaminergic response in human colon, evaluating …
motility, we aimed to characterize dopaminergic response in human colon, evaluating …
Activation of angiotensin II type 1 receptors and contractile activity in human sigmoid colon in vitro
M Mastropaolo, MG Zizzo, M Auteri… - Acta …, 2015 - Wiley Online Library
Aim To analyse the effects of angiotensin II (Ang II) on the contractility of human sigmoid
colon, and to characterize the subtype (s) of receptor (s) involved and the related action …
colon, and to characterize the subtype (s) of receptor (s) involved and the related action …
Angiotensin‐converting enzymes 1 and 2 in the feces: presence and catalytic activity in the rat 2, 4, 6‐trinitrobenzene sulfonic acid‐induced model of colitis
M Ferreira‐Duarte, LCG Oliveira… - Journal of …, 2024 - Wiley Online Library
Abstract Background and Aim Inflammatory bowel disease is challenging to diagnose. Fecal
biomarkers offer noninvasive solutions. The renin–angiotensin‐aldosterone system is …
biomarkers offer noninvasive solutions. The renin–angiotensin‐aldosterone system is …