While continuous manufacturing (CM) of pharmaceutical solid-based drug products has
been shown to be advantageous for improving the product quality and process efficiency in …

Oral solid dosage formulations and/or tablets have remained the preferred route of
administration by both patients and health care practitioners. Oral tablets are easy to …

Manufacturing of powder-based products is a focus of increasing research in the recent
years. The main reason is the lack of predictive process models connecting process …

Residence time distribution (RTD) models are essential to understand process dynamics
and support process monitoring and control in continuous manufacturing systems. RTD …

Blend uniformity was monitored throughout a continuous manufacturing (CM) process by
near infrared (NIR) spectroscopic measurements of flowing blends and compared to the …

Tablet compression has great significance in the pharmaceutical industry since most of the
drugs are in the tablet dosage form. The tablet press feed frame is used to fill powder into the …

As is the case with batch-based tableting processes, continuous tablet manufacturing can be
conducted by direct compression or with a granulation step such as dry or wet granulation …

A comprehensive commercial control strategy for tablet content and content uniformity
focussed on the unit operation of compression is presented and is proposed to enable real …

With the emergence of quality by design in the pharmaceutical industry, it becomes
imperative to gain a deeper mechanistic understanding of factors impacting the flow of a …

New analytical methods are needed to understand and optimize the processes by which
tablets are produced. Fette 3090 tablet presses are commonly used in the pharmaceutical …