The copper‐catalyzed azide/alkyne cycloaddition reaction (CuAAC) has emerged as the
most useful “click” chemistry. Polymer science has profited enormously from CuAAC by its …

CuAAC chemistry is used to compose incredible synthetic molecular architectures and acts
as a true click chemistry reaction allowing densely functional molecular fragments to be …

Click chemistry is an approach that uses efficient and reliable reactions, such as Cu (I)-
catalyzed azide–alkyne cycloaddition (CuAAC), to bind two molecular building blocks …

The ability to synthesise small peptidomimetics that mimic the secondary structure of
proteins is an ever expanding area of research directed at sourcing new medicinal agents …

Access to readily functionalized ligand architectures is of crucial importance in a range of
different areas including catalysis, metallopharmaceuticals, bioimaging …

Abstract Neuropilin-1 (NRP-1), a transmembrane glycoprotein acting as a co-receptor of
VEGF-A, is expressed by cancer and angiogenic endothelial cells and is involved in the …

We described a modification of the ionic (RADARADARADARADA) 1 peptide or RADA16-I
with 4-azidophenyl isothiocyanate via a specific and gentle reaction. The azidated peptide …

Constrained peptides pose tremendous value in drug discovery. For example, owing to their
large surface areas, they offer novel ways at inhibiting protein–protein interactions. As this …

Spiro sugar-isoxazolidines obtained by 1, 3-dipolar cycloaddition of activated exo-glycals
and nitrones were efficiently functionalized at two sites, ie C-4 and C-7, with arginine …

Five-membered heterocycles have found extensive use as peptide-and disulfide-bond
mimics in peptidomimetics. The application of 1, 4-and 1, 5-substituted 1, 2, 3-triazoles has …