Interferon-γ: teammate or opponent in the tumour microenvironment?
AM Gocher, CJ Workman, DAA Vignali - Nature Reviews Immunology, 2022 - nature.com
Cancer immunotherapy offers substantive benefit to patients with various tumour types, in
some cases leading to complete tumour clearance. However, many patients do not respond …
some cases leading to complete tumour clearance. However, many patients do not respond …
[HTML][HTML] MHC class I downregulation in cancer: underlying mechanisms and potential targets for cancer immunotherapy
AM Cornel, IL Mimpen, S Nierkens - Cancers, 2020 - mdpi.com
In recent years, major advances have been made in cancer immunotherapy. This has led to
significant improvement in prognosis of cancer patients, especially in the hematological …
significant improvement in prognosis of cancer patients, especially in the hematological …
SARS-CoV-2 vaccination enhances the effector qualities of spike-specific T cells induced by COVID-19
T cells are critical for immune protection against severe COVID-19, but it has remained
unclear whether repeated exposure to SARS-CoV-2 antigens delivered in the context of …
unclear whether repeated exposure to SARS-CoV-2 antigens delivered in the context of …
[HTML][HTML] Role of interferon-gamma (IFN-γ) and IFN-γ receptor 1/2 (IFNγR1/2) in regulation of immunity, infection, and cancer development: IFN-γ-dependent or …
H Ding, G Wang, Z Yu, H Sun, L Wang - Biomedicine & Pharmacotherapy, 2022 - Elsevier
IFN-γ, a soluble cytokine being produced by T lymphocytes, macrophages, mucosal
epithelial cells, or natural killer cells, is able to bind to the IFN-γ receptor (IFNγR) and in turn …
epithelial cells, or natural killer cells, is able to bind to the IFN-γ receptor (IFNγR) and in turn …
Bioinformatics and system biology approach to identify the influences of SARS-CoV-2 infections to idiopathic pulmonary fibrosis and chronic obstructive pulmonary …
SMH Mahmud, M Al-Mustanjid, F Akter… - Briefings in …, 2021 - academic.oup.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), better known as
COVID-19, has become a current threat to humanity. The second wave of the SARS-CoV-2 …
COVID-19, has become a current threat to humanity. The second wave of the SARS-CoV-2 …
[HTML][HTML] Molecular and cellular mechanisms of action of cannabidiol
Cannabidiol (CBD) is the primary non-psychoactive chemical from Cannabis Sativa, a plant
used for centuries for both recreational and medicinal purposes. CBD lacks the psychotropic …
used for centuries for both recreational and medicinal purposes. CBD lacks the psychotropic …
[HTML][HTML] Reparative and maladaptive inflammation in tendon healing
Tendon injuries are common and debilitating, with non-regenerative healing often resulting
in chronic disease. While there has been considerable progress in identifying the cellular …
in chronic disease. While there has been considerable progress in identifying the cellular …
[HTML][HTML] Cytokines in oncolytic virotherapy
Tumors represent a hostile environment for the effector cells of cancer immunosurveillance.
Immunosuppressive receptors and soluble or membrane-bound ligands are abundantly …
Immunosuppressive receptors and soluble or membrane-bound ligands are abundantly …
Comprehensive serum proteome profiling of cytokine release syndrome and immune effector cell–associated neurotoxicity syndrome patients with B-cell all receiving …
Purpose: To study the biology and identify markers of severe cytokine release syndrome
(CRS) and immune effector cell–associated neurotoxicity syndrome (ICANS) in children after …
(CRS) and immune effector cell–associated neurotoxicity syndrome (ICANS) in children after …
[HTML][HTML] African swine fever virus infection and cytokine response in vivo: an update
African swine fever (ASF) is a hemorrhagic viral disease of domestic pigs and wild suids (all
Sus scrofa) caused by the ASF virus (ASFV). The disease is spreading worldwide without …
Sus scrofa) caused by the ASF virus (ASFV). The disease is spreading worldwide without …