Congenital heart disease (CHD) is the most common congenital anomaly in newborn
babies. Cardiac malformations have been produced in multiple experimental animal …

Congenital heart disease is the most common congenital disorder in newborns. Advances in
cardiovascular medicine and surgery have enabled most patients to reach adulthood …

Background—Over the past decades, the life expectancy of individuals with congenital heart
disease (CHD) has increased significantly. However, precise estimates for survival to …

In the recent era, no congenital heart defect has undergone a more dramatic change in
diagnostic approach, management, and outcomes than hypoplastic left heart syndrome …

Aims Mortality in adults with congenital heart disease is known to be increased, yet its extent
and the major mortality risks are unclear. Methods and results The Dutch CONCOR national …

Background—Sudden cardiac death (SCD) is a major cause of mortality in adults with
congenital heart disease (CHD). The aim of this study was to determine the adult CHD …

Abstract Aim Patients with Marfan syndrome have an increased risk of life-threatening aortic
complications, mostly preceded by aortic dilatation. Treatment with losartan, an angiotensin …

PURPOSE: The prevalence of adult patients with congenital heart disease (CHD) has been
reported with a high degree of variability. Prevalence estimates have been calculated using …

BACKGROUND: Pulmonary arterial hypertension (PAH) associated with congenital heart
disease is usually the result of a large systemic-to-pulmonary shunt, and often leads to right …

Sudden cardiac death (SCD) accounts for up to 25% of deaths in patients with congenital
heart disease (CHD). To date, research has largely been driven by observational studies …