Tetraspanins, more than markers of extracellular vesicles in reproduction

J Jankovičová, P Sečová, K Michalková… - International Journal of …, 2020 - mdpi.com
The participation of extracellular vesicles in many cellular processes, including reproduction,
is unquestionable. Although currently, the tetraspanin proteins found in extracellular vesicles …

[HTML][HTML] Circulating microRNAs as potential biomarkers for psychiatric and neurodegenerative disorders

MMJ Van den Berg, J Krauskopf, JG Ramaekers… - Progress in …, 2020 - Elsevier
Circulating microRNAs (cimiRNAs) are a class of non-encoding RNAs found in bodily fluids
such as blood, cerebrospinal fluid (CSF) and tears. CimiRNAs have been implicated as …

A comparative study of serum exosome isolation using differential ultracentrifugation and three commercial reagents

I Helwa, J Cai, MD Drewry, A Zimmerman, MB Dinkins… - PloS one, 2017 - journals.plos.org
Exosomes play a role in cell-to-cell signaling and serve as possible biomarkers. Isolating
exosomes with reliable quality and substantial concentration is a major challenge. Our …

Mesenchymal stem cell exosomes induce proliferation and migration of normal and chronic wound fibroblasts, and enhance angiogenesis in vitro

A Shabbir, A Cox, L Rodriguez-Menocal… - Stem cells and …, 2015 - liebertpub.com
Although chronic wounds are common and continue to be a major cause of morbidity and
mortality, treatments for these conditions are lacking and often ineffective. A large body of …

[HTML][HTML] Extracellular/circulating microRNAs: release mechanisms, functions and challenges

MH Sohel - Achievements in the Life Sciences, 2016 - Elsevier
MicroRNAs (miRNAs) are endogenously initiated, small non-coding RNAs and typically
regulate the expression of mRNAs in post transcriptional level either via translational …

[HTML][HTML] Oocyte environment: follicular fluid and cumulus cells are critical for oocyte health

DA Dumesic, DR Meldrum, MG Katz-Jaffe, RL Krisher… - Fertility and sterility, 2015 - Elsevier
Bidirectional somatic cell–oocyte signaling is essential to create a changing intrafollicular
microenvironment that controls primordial follicle growth into a cohort of growing follicles …

Extracellular vesicles: roles in gamete maturation, fertilization and embryo implantation

R Machtinger, LC Laurent… - Human reproduction …, 2016 - academic.oup.com
BACKGROUND Extracellular vesicles (EVs) are membrane-bound vesicles, found in
biofluids, that carry and transfer regulatory molecules, such as microRNAs (miRNAs) and …

Mesenchymal stem cell–derived exosomes stimulate cycling quiescence and early breast cancer dormancy in bone marrow

SA Bliss, G Sinha, OA Sandiford, LM Williams… - Cancer research, 2016 - AACR
Dormant breast cancers resurge as metastatic disease after a long dormancy period in the
bone marrow, where cancer cells interact with mesenchymal stem cells (MSC). However, the …

Circulating microRNAs as biomarkers in cancer diagnosis

MMH Sohel - Life sciences, 2020 - Elsevier
MicroRNAs (miRNAs) are a group of tiny molecules of 18–22 nucleotide long noncoding
RNA that regulate the post-transcriptional gene expression through translational inhibition …

Human endometrial exosomes contain hormone-specific cargo modulating trophoblast adhesive capacity: insights into endometrial-embryo interactions

DW Greening, HPT Nguyen, K Elgass… - Biology of …, 2016 - academic.oup.com
Embryo implantation into receptive endometrium requires synergistic endometrial-blastocyst
interactions within the uterine cavity and is essential for establishing pregnancy. We …