Spinal cord injury leads to disruption in autonomic control resulting in cardiovascular, bowel,
and lower urinary tract dysfunctions, all of which significantly reduce health-related quality of …

Due to the prevalence of chronic pain worldwide, there is an urgent need to improve pain
management strategies. While opioid drugs have long been used to treat chronic pain, their …

Electrically activating mechanoreceptive afferents inhibits pain. However, paresthesia
evoked by spinal cord stimulation (SCS) at 40–60 Hz becomes uncomfortable at high pulse …

Abstract Low-frequency (< 200 Hz), subperception spinal cord stimulation (SCS) is a novel
modality demonstrating therapeutic efficacy for treating chronic neuropathic pain. When …

Objective. Spinal cord stimulation (SCS) is a common neurostimulation therapy to manage
chronic pain. Technological advances have produced new neurostimulation systems with …

Background Spinal cord stimulation (SCS) has demonstrated multiple benefits in treating
chronic pain and other clinical disorders related to sensorimotor dysfunctions. However, the …

Objective. Spinal cord neuromodulation has gained much attention for demonstrating
improved motor recovery in people with spinal cord injury, motivating the development of …

Objective. Spinal cord injury (SCI) often results in debilitating movement impairments and
neuropathic pain. Electrical stimulation of spinal neurons holds considerable promise both …

Objective. Spinal cord stimulation (SCS) is a common treatment for chronic pain. For
decades, SCS maximized overlap between stimulation-induced paresthesias and the …

The neurophysiological effects of spinal cord stimulation (SCS) for chronic pain are poorly
understood, resulting in inefficient failure-prone programming protocols and inadequate …