Tumour-associated mesenchymal stem/stromal cells: emerging therapeutic targets

Y Shi, L Du, L Lin, Y Wang - Nature reviews Drug discovery, 2017 - nature.com
Mesenchymal stem cells, also known as mesenchymal stromal cells (MSCs), exist in many
tissues and are known to actively migrate to sites of tissue injury, where they participate in …

Endothelial progenitor cells: characterization and role in vascular biology

C Urbich, S Dimmeler - Circulation research, 2004 - Am Heart Assoc
Infusion of different hematopoietic stem cell populations and ex vivo expanded endothelial
progenitor cells augments neovascularization of tissue after ischemia and contributes to …

Marrow-derived stromal cells express genes encoding a broad spectrum of arteriogenic cytokines and promote in vitro and in vivo arteriogenesis through paracrine …

T Kinnaird, E Stabile, MS Burnett, CW Lee… - Circulation …, 2004 - Am Heart Assoc
We recently demonstrated that marrow stromal cells (MSCs) augment collateral remodeling
through release of several cytokines such as VEGF and bFGF rather than via cell …

Mesenchymal stem/stromal cells as a pharmacological and therapeutic approach to accelerate angiogenesis

A Bronckaers, P Hilkens, W Martens, P Gervois… - Pharmacology & …, 2014 - Elsevier
Mesenchymal stem cells or multipotent stromal cells (MSCs) have initially captured attention
in the scientific world because of their differentiation potential into osteoblasts …

Concise review: dissecting a discrepancy in the literature: do mesenchymal stem cells support or suppress tumor growth?

AH Klopp, A Gupta, E Spaeth, M Andreeff… - Stem cells, 2011 - academic.oup.com
The discovery that mesenchymal stem cells (MSCs) are recruited into tumors has led to a
great deal of interest over the past decade in the function of MSCs in tumors. To address …

Transplantation of mesenchymal stem cells improves cardiac function in a rat model of dilated cardiomyopathy

N Nagaya, K Kangawa, T Itoh, T Iwase, S Murakami… - Circulation, 2005 - Am Heart Assoc
Background—Pluripotent mesenchymal stem cells (MSCs) differentiate into a variety of cells,
including cardiomyocytes and vascular endothelial cells. However, little information is …

Bone marrow-derived mesenchymal stem cells and the tumor microenvironment

SA Bergfeld, YA DeClerck - Cancer and Metastasis Reviews, 2010 - Springer
Over the last decade, there has been a growing interest in the role of mesenchymal stem
cells (MSC) in cancer progression. These cells have the potential to give rise to a variety of …

Intravenous administration of mesenchymal stem cells improves cardiac function in rats with acute myocardial infarction through angiogenesis and myogenesis

N Nagaya, T Fujii, T Iwase, H Ohgushi… - American Journal …, 2004 - journals.physiology.org
Mesenchymal stem cells (MSCs) are pluripotent cells that differentiate into a variety of cells,
including cardiomyocytes and endothelial cells. However, little information is available …

Concentration-dependent inhibition of angiogenesis by mesenchymal stem cells

K Otsu, S Das, SD Houser, SK Quadri… - Blood, The Journal …, 2009 - ashpublications.org
Mesenchymal stem cells (MSCs), which potentially transdifferentiate into multiple cell types,
are increasingly reported to be beneficial in models of organ system injury. However, the …

Targeting nonhealing ulcers of lower extremity in human through autologous bone marrow-derived mesenchymal stem cells

NR Dash, SN Dash, P Routray, S Mohapatra… - Rejuvenation …, 2009 - liebertpub.com
Bone marrow (BM)-derived mesenchymal stem cells (MSCs) represent a promising
population for supporting new concepts in cellular therapy. This study was undertaken to …