Opsonization, biodistribution, and pharmacokinetics of polymeric nanoparticles

DE Owens III, NA Peppas - International journal of pharmaceutics, 2006 - Elsevier
The process of opsonization is one of the most important biological barriers to controlled
drug delivery. Injectable polymeric nanoparticle carriers have the ability to revolutionize …

Structure and design of polymeric surfactant-based drug delivery systems

VP Torchilin - Journal of controlled release, 2001 - Elsevier
The review concentrates on the use of polymeric micelles as pharmaceutical carriers.
Micellization of biologically active substances is a general phenomenon that increases the …

Multifunctional nanocarriers

VP Torchilin - Advanced drug delivery reviews, 2006 - Elsevier
Currently used pharmaceutical nanocarriers, such as liposomes, micelles, nanoemulsions,
polymeric nanoparticles and many others demonstrate a broad variety of useful properties …

Surface modification of nanoparticles to oppose uptake by the mononuclear phagocyte system

G Storm, SO Belliot, T Daemen, DD Lasic - Advanced drug delivery reviews, 1995 - Elsevier
An overview of recent advances in the surface modification of colloidal particles to oppose
uptake by the mononuclear phagocyte system (MPS) is presented. First, we describe the …

Stealth properties to improve therapeutic efficacy of drug nanocarriers

S Salmaso, P Caliceti - Journal of drug delivery, 2013 - Wiley Online Library
Over the last few decades, nanocarriers for drug delivery have emerged as powerful tools
with unquestionable potential to improve the therapeutic efficacy of anticancer drugs. Many …

Targeted pharmaceutical nanocarriers for cancer therapy and imaging

VP Torchilin - The AAPS journal, 2007 - Springer
The use of various pharmaceutical nanocarriers has become one of the most important
areas of nanomedicine. Ideally, such carriers should be specifically delivered (targeted) to …

Stabilization and functionalization of iron oxide nanoparticles for biomedical applications

E Amstad, M Textor, E Reimhult - Nanoscale, 2011 - pubs.rsc.org
Superparamagnetic iron oxide nanoparticles (NPs) are used in a rapidly expanding number
of research and practical applications in the biomedical field, including magnetic cell …

The effect of PEGylation of mesoporous silica nanoparticles on nonspecific binding of serum proteins and cellular responses

Q He, J Zhang, J Shi, Z Zhu, L Zhang, W Bu, L Guo… - Biomaterials, 2010 - Elsevier
Highly ordered MCM-41-type mesoporous silica nanoparticles (MSNs) with particle sizes of
150±20 nm were prepared and PEGylated by covalently grafting PEGxk chains of different …

In vitro assessments of nanomaterial toxicity

CF Jones, DW Grainger - Advanced drug delivery reviews, 2009 - Elsevier
Nanotechnology has grown from a scientific interest to a major industry with both commodity
and specialty nanomaterial exposure to global populations and ecosystems. Sub-micron …

Blood compatibility of polyethylene oxide surfaces

JH Lee, HB Lee, JD Andrade - Progress in polymer science, 1995 - Elsevier
General features Solubility and molecular structure of PEO in water Solubility vs temperature
mobility Heat and entropy of dilution Comparison with some other polymers 2.6. 1 …