Intracellular delivery is a key step in biological research and has enabled decades of
biomedical discoveries. It is also becoming increasingly important in industrial and medical …

Over the past few decades, gene therapy has gained immense importance in medical
research as a promising treatment strategy for diseases such as cancer, AIDS, Alzheimer's …

Gene editing is a versatile technique in biomedicine that promotes fundamental research as
well as clinical therapy. The development of Clustered Regularly Interspaced Short …

Engineering vaccine-based therapeutics for infectious diseases is highly challenging, as
trial formulations are often found to be nonspecific, ineffective, thermally or hydrolytically …

Nuclear transfection of DNA into mammalian cells is challenging yet critical for many
biological and medical studies. Here, by combining cell squeezing and electric-field-driven …

The recently developed CRISPR/Cas9 technology has revolutionized the genome
engineering field. Since 2016, increasing number of studies regarding CRISPR therapeutics …

Two-dimensional nanomaterials are emerging as promising candidates for a wide range of
biomedical applications including tissue engineering, biosensing, pathogen incapacitation …

The burden of cancer is increasing globally. Several challenges facing its mainstream
treatment approaches have formed the basis for the development of targeted delivery …

Besides its broad application in research and biotechnology, genome editing (GE) has great
potential for clinical gene therapy, but delivery of GE tools remains a bottleneck. Whereas …

Gene delivery as a promising and valid tool has been used for treating many serious
diseases that conventional drug therapies cannot cure. Due to the advancement of physical …