Leak currents, defined as voltage and time independent flows of ions across cell
membranes, are central to cellular electrical excitability control. The K 2P (KCNK) potassium …

Store-operated channels (SOCs) are highly selective Ca2+ channels that mediate Ca2+
influx in non-excitable and excitable (ie, skeletal and cardiac muscle) cells. These channels …

Store-operated calcium entry (SOCE) through the Ca2+ release–activated Ca2+ (CRAC)
channel is a central mechanism by which cells generate Ca2+ signals and mediate Ca2+ …

The calcium-release-activated calcium (CRAC) channel, activated by the release of Ca2+
from the endoplasmic reticulum (ER), is critical for Ca2+ homeostasis and active signal …

Calcium (Ca2+) signaling plays a dichotomous role in cellular biology, controlling cell
survival and proliferation on the one hand and cellular toxicity and cell death on the other …

Abstract Store-operated Ca2+ entry (SOCE) is a major pathway for calcium signaling, which
regulates almost every biological process, involving cell proliferation, differentiation …

ALG-2 is a penta-EF-hand Ca2+-binding protein and interacts with a variety of proteins in
mammalian cells. In order to find new ALG-2-binding partners, we searched a human …

Abstract Ral Guanine Nucleotide Dissociation Stimulator Like 1 (RGL1) is a RAS effector
protein that activates Ral GTPase by stimulating nucleotide exchange. Most structures of …

Store-operated calcium entry (SOCE) is involved in the pathogenesis of airway inflammation
and remodeling in asthma. Store-operated calcium entry-associated regulatory factor …

Store-operated calcium entry (SOCE) is a vital process aimed at refilling cellular internal
Ca2+ stores and a primary cellular signaling driver for transcription factors' entry to the …