Mammalian models including non‐human primates, pigs and rodents have been used
extensively to study the mechanisms of cardiovascular disease. However, there is an …

Tests with zebrafish embryos have gained wide acceptance as an alternative test model for
drug development and toxicity testing. In particular, the behavioral response of the zebrafish …

Background: Per-and polyfluoroalkyl substances (PFAS) are a diverse class of industrial
chemicals with widespread environmental occurrence. Exposure to long-chain PFAS is …

This work reports an integrated nanosafety study including the synthesis and
characterization of the graphene oxide-silver nanoparticle hybrid material (GO-AgNPs) and …

As an important part in international disease, mental disorders seriously damage human
health and social stability, which show the complex pathogenesis and increasing incidence …

Globally, millions of zebrafish (Danio rerio) are used for scientific laboratory experiments for
which researchers have a duty of care, with legal obligations to consider their welfare …

Textile microfibers are the most common form of microplastic pollution and among the most
dangerous to wildlife across multiple biomes. Besides toxicological challenges arising from …

Melanogenesis is a biosynthetic pathway for the formation of the pigment melanin in human
skin. A key enzyme in the process of pigmentation through melanin is tyrosinase, which …

A major goal of translational toxicology is to identify adverse chemical effects and determine
whether they are conserved or divergent across experimental systems. Translational …

The use of larval zebrafish developmental testing and assessment, specifically larval
zebrafish locomotor activity, has been recognized as a higher throughput testing strategy to …