[HTML][HTML] Biomarkers in the diagnosis of pancreatic cancer: Are we closer to finding the golden ticket?
RS O'Neill, A Stoita - World journal of gastroenterology, 2021 - ncbi.nlm.nih.gov
Pancreatic cancer (PC) is a leading cause of cancer related mortality on a global scale. The
disease itself is associated with a dismal prognosis, partly due to its silent nature resulting in …
disease itself is associated with a dismal prognosis, partly due to its silent nature resulting in …
Is tumour-expressed aminopeptidase N (APN/CD13) structurally and functionally unique?
FM Barnieh, PM Loadman, RA Falconer - Biochimica et Biophysica Acta …, 2021 - Elsevier
Abstract Aminopeptidase N (APN/CD13) is a multifunctional glycoprotein that acts as a
peptidase, receptor, and signalling molecule in a tissue-dependent manner. The activities of …
peptidase, receptor, and signalling molecule in a tissue-dependent manner. The activities of …
Design of aminopeptidase N inhibitors as anti-cancer agents
Aminopeptidase N (APN) is an important metalloenzyme. It regulates multivariate cellular
functions by different mechanisms such as enzymatic cleavage of peptides. This may play a …
functions by different mechanisms such as enzymatic cleavage of peptides. This may play a …
Evaluation of an Integrin αvβ3 and Aminopeptidase N Dual-Receptor Targeting Tracer for Breast Cancer Imaging
Y Gai, Y Jiang, Y Long, L Sun, Q Liu, C Qin… - Molecular …, 2019 - ACS Publications
Integrin αvβ3 and aminopeptidase N (APN, also known as CD13) are two important targets
involved in the regulation of angiogenesis, tumor proliferation, invasion, and metastasis. In …
involved in the regulation of angiogenesis, tumor proliferation, invasion, and metastasis. In …
Review of immunohistochemistry biomarkers in pancreatic cancer diagnosis
TT Luu - Frontiers in Oncology, 2021 - frontiersin.org
Pancreatic cancer is one of the cancer types with poor prognosis and high rate of mortality.
Diagnostic modalities for early detection of pancreatic cancer have been among the …
Diagnostic modalities for early detection of pancreatic cancer have been among the …
Molecular imaging of angiogenesis in oncology: current preclinical and clinical status
A Florea, FM Mottaghy, M Bauwens - International journal of molecular …, 2021 - mdpi.com
Angiogenesis is an active process, regulating new vessel growth, and is crucial for the
survival and growth of tumours next to other complex factors in the tumour …
survival and growth of tumours next to other complex factors in the tumour …
Molecular imaging of aminopeptidase N in cancer and angiogenesis
CL Schreiber, BD Smith - Contrast media & molecular imaging, 2018 - Wiley Online Library
This review focuses on recent advances in the molecular imaging of aminopeptidase N
(APN, also known as CD13), a zinc metalloenzyme that cleaves N‐terminal neutral amino …
(APN, also known as CD13), a zinc metalloenzyme that cleaves N‐terminal neutral amino …
Development of a novel latent electrochemical molecular substrate for the real-time monitoring of the tumor marker aminopeptidase N in live cells, whole blood and …
S Kumaravel, GR Luo, ST Huang, HY Lin… - Biosensors and …, 2022 - Elsevier
Abstract Aminopeptidase N (APN/CD13) plays an important role in the growth and
metastasis, of tumor, and is a potential biomarker for the post-treatment surveillance of …
metastasis, of tumor, and is a potential biomarker for the post-treatment surveillance of …
Expression and activity of angiotensin-regulating enzymes is associated with prognostic outcome in clear cell renal cell carcinoma patients
P Errarte, M Beitia, I Perez, L Manterola, CH Lawrie… - PloS one, 2017 - journals.plos.org
The discovery of the intrarenal renin-angiotensin system (iRAS), which regulates
angiogenesis, cell differentiation and proliferation, has opened new perspectives in the …
angiogenesis, cell differentiation and proliferation, has opened new perspectives in the …
Simple and sensitive electrochemical detection of aminopeptidase N using monolayer-modified Au interdigitated array electrodes with moderate electrocatalytic …
Electrochemical–electrochemical (EE) redox cycling using interdigitated array (IDA)
electrodes is a simple and efficient approach for signal amplification. However, IDA …
electrodes is a simple and efficient approach for signal amplification. However, IDA …