Mitochondrial ROS, ER stress, and Nrf2 crosstalk in the regulation of mitochondrial apoptosis induced by arsenite
Long-term ingestion of arsenicals, a heterogeneous group of toxic compounds, has been
associated with a wide spectrum of human pathologies, which include various malignancies …
associated with a wide spectrum of human pathologies, which include various malignancies …
Positive association of cardiovascular disease (CVD) with chronic exposure to drinking water arsenic (As) at concentrations below the WHO provisional guideline …
To the best of our knowledge, a dose-response meta-analysis of the relationship between
cardiovascular disease (CVD) and arsenic (As) exposure at drinking water As …
cardiovascular disease (CVD) and arsenic (As) exposure at drinking water As …
Six months exposure to a real life mixture of 13 chemicals' below individual NOAELs induced non monotonic sex-dependent biochemical and redox status changes in …
This study assessed the potential adverse health effects of long-term low-dose exposure to
chemical mixtures simulating complex real-life human exposures. Four groups of Sprague …
chemical mixtures simulating complex real-life human exposures. Four groups of Sprague …
An updated systematic review and dose-response meta-analysis on the relation between exposure to arsenic and risk of type 2 diabetes
NR Kakavandi, T Mousavi, T Asadi, A Moradi… - Toxicology letters, 2023 - Elsevier
Arsenic is among the most critical environmental toxicants associated with many human
disorders. However, its effect on type 2 diabetes mellitus (T2DM) is contradictory. This …
disorders. However, its effect on type 2 diabetes mellitus (T2DM) is contradictory. This …
G3BP1-linked mRNA partitioning supports selective protein synthesis in response to oxidative stress
SP Somasekharan, F Zhang, N Saxena… - Nucleic acids …, 2020 - academic.oup.com
Cells limit energy-consuming mRNA translation during stress to maintain metabolic
homeostasis. Sequestration of mRNAs by RNA binding proteins (RBPs) into RNA granules …
homeostasis. Sequestration of mRNAs by RNA binding proteins (RBPs) into RNA granules …
Hypoxia enhances endothelial intercellular adhesion molecule 1 protein level through upregulation of arginase type II and mitochondrial oxidative stress
X Liang, P Arullampalam, Z Yang, XF Ming - Frontiers in physiology, 2019 - frontiersin.org
Hypoxia plays a crucial role in the pathogenesis of cardiovascular diseases. Mitochondrial
enzyme arginase type II (Arg-II) is reported to lead to endothelial dysfunction and enhance …
enzyme arginase type II (Arg-II) is reported to lead to endothelial dysfunction and enhance …
Mitochondria in the Spotlight: C. elegans as a Model Organism to Evaluate Xenobiotic-Induced Dysfunction
Mitochondria play a crucial role in cellular respiration, ATP production, and the regulation of
various cellular processes. Mitochondrial dysfunctions have been directly linked to …
various cellular processes. Mitochondrial dysfunctions have been directly linked to …
[HTML][HTML] Association of low-level inorganic arsenic exposure from rice with age-standardized mortality risk of cardiovascular disease (CVD) in England and Wales
Adverse health outcomes, including death from cardiovascular disease (CVD), arising from
chronic exposure to inorganic arsenic (iAs) are well documented. Consumption of rice is a …
chronic exposure to inorganic arsenic (iAs) are well documented. Consumption of rice is a …
Mitochondrial oxidative stress is the general reason for apoptosis induced by different-valence heavy metals in cells and mitochondria
SM Korotkov - International Journal of Molecular Sciences, 2023 - mdpi.com
This review analyzes the causes and consequences of apoptosis resulting from oxidative
stress that occurs in mitochondria and cells exposed to the toxic effects of different-valence …
stress that occurs in mitochondria and cells exposed to the toxic effects of different-valence …
Alternol eliminates excessive ATP production by disturbing Krebs cycle in prostate cancer
C Li, C He, Y Xu, H Xu, Y Tang, H Chavan… - The …, 2019 - Wiley Online Library
Background Alternol is a natural compound isolated from fermentation products of a mutant
fungus. Our previous studies demonstrated that Alternol specifically kills cancer cells but …
fungus. Our previous studies demonstrated that Alternol specifically kills cancer cells but …