[HTML][HTML] Neutrophil elastase and chronic lung disease

JA Voynow, M Shinbashi - Biomolecules, 2021 - mdpi.com
Neutrophil elastase (NE) is a major inflammatory protease released by neutrophils and is
present in the airways of patients with cystic fibrosis (CF), chronic obstructive pulmonary …

Flavonoids regulate tumor-associated macrophages–from structure-activity relationship to clinical potential

Q Sun, Q Liu, X Zhou, X Wang, H Li, W Zhang… - Pharmacological …, 2022 - Elsevier
In recent years, the strategy for tumor therapy has changed from focusing on the direct killing
effect of different types of therapeutic agents on cancer cells to the new mainstream of multi …

Flavonoids as tyrosinase inhibitors in in silico and in vitro models: basic framework of SAR using a statistical modelling approach

K Jakimiuk, S Sari, R Milewski… - Journal of Enzyme …, 2022 - Taylor & Francis
Flavonoids are widely distributed in plants and constitute the most common polyphenolic
phytoconstituents in the human diet. In this study, the in vitro inhibitory activity of 44 different …

[HTML][HTML] Phytochemistry and pharmacology of natural prenylated flavonoids

HW Lv, QL Wang, M Luo, MD Zhu, HM Liang… - Archives of Pharmacal …, 2023 - Springer
Prenylated flavonoids are a special kind of flavonoid derivative possessing one or more
prenyl groups in the parent nucleus of the flavonoid. The presence of the prenyl side chain …

[HTML][HTML] Antiviral and Immunomodulatory Effects of Pelargonium sidoides DC. Root Extract EPs® 7630 in SARS-CoV-2-Infected Human Lung Cells

J Papies, J Emanuel, N Heinemann, Ž Kulić… - Frontiers in …, 2021 - frontiersin.org
Treatment options for COVID-19 are currently limited. Drugs reducing both viral loads and
SARS-CoV-2-induced inflammatory responses would be ideal candidates for COVID-19 …

[HTML][HTML] Inhibition of dipeptidyl peptidase-4 by flavonoids: Structure–activity relationship, kinetics and interaction mechanism

J Pan, Q Zhang, C Zhang, W Yang, H Liu, Z Lv… - Frontiers in …, 2022 - frontiersin.org
With the aim to establish a structure-inhibitory activity relationship of flavonoids against
dipeptidyl peptidase-4 (DPP-4) and elucidate the interaction mechanisms between them, a …

[HTML][HTML] Radiation from UV-A to red light induces ROS-dependent release of neutrophil extracellular traps

G Arzumanyan, K Mamatkulov, Y Arynbek… - International journal of …, 2023 - mdpi.com
Neutrophils release decondensed chromatin or extracellular traps (NETs) in response to
various physiological and pharmacological stimuli. Apart from host defensive functions …

[HTML][HTML] Bioactive compounds, anti-inflammatory, anti-nociceptive and antioxidant potentials of ethanolic leaf fraction of Sida linifolia L.(Malvaceae)

NE Nwankwo, EC Ezeako, FN Nworah… - Arabian Journal of …, 2023 - Elsevier
This study investigated the bioactive compounds, anti-inflammatory, anti-nociceptive, and
antioxidant properties of the ethanolic leaf fraction of Sida linifolia (ELFSL). The in vitro anti …

Naringenin as a possible candidate against SARS-CoV-2 infection and in the pathogenesis of COVID-19

PK Agrawal, C Agrawal… - Natural Product …, 2021 - journals.sagepub.com
Naringenin, widely distributed in fruits and vegetables, is endowed with antiviral and other
health beneficial activities, such as immune-stimulating and anti-inflammatory actions that …

[HTML][HTML] Allergic inflammation: Effect of propolis and its flavonoids

N Oršolić - Molecules, 2022 - mdpi.com
The incidence of allergic diseases and their complications are increasing worldwide. Today,
people increasingly use natural products, which has been termed a “return to nature” …