Voltage-gated potassium channels as regulators of cell death

M Bachmann, W Li, MJ Edwards, SA Ahmad… - Frontiers in cell and …, 2020 - frontiersin.org
Ion channels allow the flux of specific ions across biological membranes, thereby
determining ion homeostasis within the cells. Voltage-gated potassium-selective ion …

Effects of boron-containing compounds on immune responses: review and patenting trends

KS Romero-Aguilar, IM Arciniega-Martínez… - Expert Opinion on …, 2019 - Taylor & Francis
Introduction: Boron-containing compounds induce effects on immune responses. Such
effects are interesting to the biomedical field for the development of therapeutic tools to …

Transient receptor potential ankyrin1 channel is endogenously expressed in T cells and is involved in immune functions

SS Sahoo, RK Majhi, A Tiwari, T Acharya… - Bioscience …, 2019 - portlandpress.com
Transient receptor potential channel subfamily A member 1 (TRPA1) is a non-selective
cationic channel, identified initially as a cold sensory receptor. TRPA1 responds to diverse …

Modulation of adaptive immunity and viral infections by ion channels

K Bohmwald, NMS Gálvez, CA Andrade… - Frontiers in …, 2021 - frontiersin.org
Most cellular functions require of ion homeostasis and ion movement. Among others, ion
channels play a crucial role in controlling the homeostasis of anions and cations …

The Voltage-Gated Hv1 H+ Channel Is Expressed in Tumor-Infiltrating Myeloid-Derived Suppressor Cells

M Cozzolino, A Gyöngyösi, E Korpos… - International Journal of …, 2023 - mdpi.com
Myeloid-derived suppressor cells (MDSCs) are key determinants of the immunosuppressive
microenvironment in tumors. As ion channels play key roles in the physiology …

High throughput clone screening on overexpressed hERG1 and Kv1. 3 potassium channels using ion channel reader (ICR) label free technology

A Montalbano, C Sala, GC Altadonna, A Becchetti… - Heliyon, 2023 - cell.com
Pharmacological studies aimed at the development of newly synthesized drugs directed
against ion channels (as well as genetic studies of ion channel mutations) involve the …

7DHC-induced changes of Kv1. 3 operation contributes to modified T cell function in Smith-Lemli-Opitz syndrome

A Balajthy, S Somodi, Z Pethő, M Péter, Z Varga… - … -European Journal of …, 2016 - Springer
In vitro manipulation of membrane sterol level affects the regulation of ion channels and
consequently certain cellular functions; however, a comprehensive study that confirms the …

Immunomagnetic separation is a suitable method for electrophysiology and ion channel pharmacology studies on T cells

G Tajti, TG Szanto, A Csoti, G Racz, C Evaristo… - Channels, 2021 - Taylor & Francis
Ion channels play pivotal role in the physiological and pathological function of immune cells.
As immune cells represent a functionally diverse population, subtype-specific functional …

Rapid quantification of mitogen-induced blastogenesis in T lymphocytes for identifying immunomodulatory drugs

JN Gibson, P Beesetty, C Sulentic, JA Kozak - JoVE (Journal of Visualized …, 2016 - jove.com
Lymphocyte proliferation in response to antigenic or mitogenic stimulation is a readily
quantifiable phenomenon useful for testing immunomodulatory (ie, immunosuppressive or …

[PDF][PDF] 7DHC-induced changes of Kv1. 3 operation contributes to modified T cell function in Smith-Lemli-Opitz syndrome

P Hajdu - core.ac.uk
In vitro manipulation of membrane sterol level affects the regulation of ion channels and
consequently certain cellular functions, however, a comprehensive study that confirms the …