Crystallization is one of the most important unit operations used for the separation and
purification of crystalline solid products. Appropriate design and control of the crystallization …

In an industrial crystallization process, crystal shape strongly influences end-product quality
and functionality, as well as downstream processing. In addition, nucleation events, solvent …

Crystal morphology is known to be of great importance to the end-use properties of crystal
products, and to affect down-stream processing such as filtration and drying. However, it has …

A continuously seeded l-glutamic acid cooling crystallization process, in a continuous
oscillatory baffled crystallizer, was designed and operated to deliver control over …

The evolution of particle shape is an important consideration in many industrial
crystallizations. This article describes the design of temperature-cycling experiments …

The crystallisation of ibuprofen under diffusion-limited conditions measured as a function of
supersaturation, solvent (95% ethanol/water, ethyl acetate, acetonitrile and toluene) and …

Morphological population balance (PB) modeling of crystallization processes predicts the
dynamic evolution of shape distribution of crystals grown from solution. It requires growth …

Crystal size estimation from in situ images has received attention recently as a means to
estimate product properties in real-time. In this paper, an automated image analysis strategy …

Two-dimensional (2D) crystals, for which the shape is described by two linear sizes, are
common in fine chemical and pharmaceutical industries. Since the crystal size and shape …

Multidimensional population balance models (PBMs) describe chemical and biological
processes having a distribution over two or more intrinsic properties (such as size and age …