Cholangiocarcinoma (CCA) includes a cluster of highly heterogeneous biliary malignant
tumours that can arise at any point of the biliary tree. Their incidence is increasing globally …

The WNT/β-catenin signaling pathway is a highly conserved and tightly controlled molecular
mechanism that regulates embryonic development, cellular proliferation and differentiation …

The canonical Wnt–β-catenin pathway is a complex, evolutionarily conserved signalling
mechanism that regulates fundamental physiological and pathological processes. Wnt–β …

Wnt signaling is one of the key cascades regulating development and stemness, and has
also been tightly associated with cancer. The role of Wnt signaling in carcinogenesis has …

Cholangiocarcinoma (CCA) is a heterogeneous group of malignancies with features of
biliary tract differentiation. CCA is the second most common primary liver tumour and the …

Cholangiocarcinoma (CCA) is a malignancy with features of the biliary epithelium. Although
CCA is recognized as a rare cancer, it is the second most common primary liver tumor after …

This study investigated the exosomal circular RNAs (CircRNAs) produced by tumor-
associated macrophages and delivered into the microenvironment of cholangiocarcinoma …

Liver cancer is among the leading global healthcare issues associated with high morbidity
and mortality. Liver cancer consists of hepatocellular carcinoma (HCC), cholangiocarcinoma …

The release of reactive oxygen species (ROS) and the generation of oxidative stress are
considered critical factors for the pathogenesis of diabetes mellitus (DM), a disorder that is …

Intrahepatic cholangiocarcinoma (iCCA) is a molecularly heterogeneous hepatobiliary
neoplasm with poor prognosis and limited therapeutic options. The incidence of this …