Biogenic synthesis of zinc oxide nanoparticles using mushroom fungus Cordyceps militaris: Characterization and mechanistic insights of therapeutic investigation

C Dias, M Ayyanar, S Amalraj, P Khanal… - Journal of Drug Delivery …, 2022 - Elsevier
The present research demonstrates the Cordyceps militaris (a medicinal mushroom)
mediated fabrication of zinc oxide nanoparticles (Cor-ZnONPs) and its therapeutic …

Pteroyl-γ-l-glutamate/Pluronic® F68 modified polymeric micelles loaded with docetaxel for targeted delivery and reduced toxicity

N Rarokar, R Agrawal, S Yadav, P Khedekar… - Journal of Molecular …, 2023 - Elsevier
Targeting the cancerous cells is essential to improve the drug's efficacy and avoid toxicity to
normal cells, which can be achieved by surface functionalizing the nanocarriers like …

Fabrication of chitosan nanocomposites loaded with biosynthetic metallic nanoparticles and their therapeutic investigation

S Gracias, M Ayyanar, G Peramaiyan, M Kalaskar… - Environmental …, 2023 - Elsevier
The present research demonstrates the formation of zinc oxide nanoparticles facilitated by
Cissus quadrangularis (CQ-ZnONPs) and subsequent synthesis of chitosan-conjugated …

[HTML][HTML] QBD approach for the development of hesperetin loaded colloidal nanosponges for sustained delivery: In-vitro, ex-vivo, and in-vivo assessment

K Rodrigues, S Nadaf, N Rarokar, N Gurav, P Jagtap… - OpenNano, 2022 - Elsevier
Hesperetin (HT) is a polyphenolic compound with anti-carcinogenic, tumor necrosis, and
anti-oxidant properties. The present study reports the fabrication, optimization, and …

Preparation and formula optimization of cephalexin loaded transferosomal gel by QbD to enhance the transdermal delivery: in vitro, ex vivo and in vivo study

NR Rarokar, SD Saoji, NV Deole, M Gaikwad… - Journal of Drug Delivery …, 2023 - Elsevier
Most antibiotics used in topical formulations are not absorbed by deeper skin layers and
subdermal tissues. Hence the skin infections are treated with large doses of oral or …

Process Optimization for the Bioinspired Synthesis of Gold Nanoparticles Using Cordyceps militaris, Its Characterization, and Assessment of Enhanced Therapeutic …

G Gawas, M Ayyanar, N Gurav, D Hase, V Murade… - Pharmaceuticals, 2023 - mdpi.com
The promising therapeutic implications of nanoparticles have spurred their development for
biomedical applications. An eco-friendly methodology synthesizes gold nanoparticles using …

Design and optimization of chitosan-coated solid lipid nanoparticles containing insulin for improved intestinal permeability using piperine

I Raghunath, M Koland, C Sarathchandran… - International Journal of …, 2024 - Elsevier
The objective of this research was to optimize the composition and performance of chitosan-
coated solid lipid nanoparticles carrying insulin (Ch-In-SLNs) and to assess the potential of …

QBD approach for the design, optimization, development, and characterization of naringenin-loaded phytosomes to enhance solubility and oral bioavailability

V Metkari, R Shah, N Salunkhe, S Gurav - Journal of Pharmaceutical …, 2023 - Springer
Purpose The design, optimization, preparation, and characterization of phytosomes loaded
with naringenin were the goals of the current work. The present work was intended to …

Membrane Permeability and Drug Targeting Potential of Phospholipid‐Based Nanocarriers in Lung Cancer Therapy

O Sen, P Sarkar, S Das, NK Giri, S Sarkar… - …, 2024 - Wiley Online Library
Lung cancer has become the leading cause of cancer‐related deaths, surpassing all other
forms of cancer. Among lung cancers, non‐small cell lung cancer (NSCLC) accounts for …

Comparative assessment of solubility enhancement of itroconazole by solid dispersion and co-crystallization technique: Investigation of simultaneous effect of media …

K Rajbhar, GR Karodadeo, V Kumar… - Annales …, 2023 - Elsevier
Solubility of the drug is an important property of the drug as it affects the release, absorption,
dissolution rate and ultimately bioavailability of the drug. Hence, the poorly aqueous soluble …