A dendrite-focused framework for understanding the actions of ketamine and psychedelics
NK Savalia, LX Shao, AC Kwan - Trends in neurosciences, 2021 - cell.com
Pilot studies have hinted that serotonergic psychedelics such as psilocybin may relieve
depression, and could possibly do so by promoting neural plasticity. Intriguingly, another …
depression, and could possibly do so by promoting neural plasticity. Intriguingly, another …
[HTML][HTML] Deep-brain optical recording of neural dynamics during behavior
In vivo fluorescence recording techniques have produced landmark discoveries in
neuroscience, providing insight into how single cell and circuit-level computations mediate …
neuroscience, providing insight into how single cell and circuit-level computations mediate …
[HTML][HTML] A rise-to-threshold process for a relative-value decision
Whereas progress has been made in the identification of neural signals related to rapid,
cued decisions,–, less is known about how brains guide and terminate more ethologically …
cued decisions,–, less is known about how brains guide and terminate more ethologically …
A database and deep learning toolbox for noise-optimized, generalized spike inference from calcium imaging
P Rupprecht, S Carta, A Hoffmann, M Echizen… - Nature …, 2021 - nature.com
Inference of action potentials ('spikes') from neuronal calcium signals is complicated by the
scarcity of simultaneous measurements of action potentials and calcium signals ('ground …
scarcity of simultaneous measurements of action potentials and calcium signals ('ground …
Adaptive stimulus selection for consolidation in the hippocampus
Associative memories guide behavioural adaptation by binding together outcome-predictive
sensory stimuli,. However, in a feature-rich environment, only a subset of stimuli may predict …
sensory stimuli,. However, in a feature-rich environment, only a subset of stimuli may predict …
[HTML][HTML] A non-canonical striatopallidal Go pathway that supports motor control
In the classical model of the basal ganglia, direct pathway striatal projection neurons
(dSPNs) send projections to the substantia nigra (SNr) and entopeduncular nucleus to …
(dSPNs) send projections to the substantia nigra (SNr) and entopeduncular nucleus to …
[HTML][HTML] Neuromorphic-based neuroprostheses for brain rewiring: state-of-the-art and perspectives in neuroengineering
Neuroprostheses are neuroengineering devices that have an interface with the nervous
system and supplement or substitute functionality in people with disabilities. In the collective …
system and supplement or substitute functionality in people with disabilities. In the collective …
Activity of a direct VTA to ventral pallidum GABA pathway encodes unconditioned reward value and sustains motivation for reward
WL Zhou, K Kim, F Ali, ST Pittenger, CA Calarco… - Science …, 2022 - science.org
Dopamine signaling from the ventral tegmental area (VTA) plays critical roles in reward-
related behaviors, but less is known about the functions of neighboring VTA GABAergic …
related behaviors, but less is known about the functions of neighboring VTA GABAergic …
[HTML][HTML] Neurons learn by predicting future activity
Understanding how the brain learns may lead to machines with human-like intellectual
capacities. It was previously proposed that the brain may operate on the principle of …
capacities. It was previously proposed that the brain may operate on the principle of …
[HTML][HTML] Nanostructured gold electrodes promote neural maturation and network connectivity
Progress in the clinical application of recording and stimulation devices for neural diseases
is still limited, mainly because of suboptimal material engineering and unfavorable …
is still limited, mainly because of suboptimal material engineering and unfavorable …