Epidemiology and disease burden of tuberculosis in children: a global perspective
JA Seddon, D Shingadia - Infection and drug resistance, 2014 - Taylor & Francis
Our understanding of the tuberculosis (TB) epidemic in children is incomplete due to
challenges in diagnosis and reporting. Children have also been largely excluded from …
challenges in diagnosis and reporting. Children have also been largely excluded from …
Tuberculosis susceptibility and protection in children
Children represent both a clinically important population susceptible to tuberculosis and a
key group in whom to study intrinsic and vaccine-induced mechanisms of protection. After …
key group in whom to study intrinsic and vaccine-induced mechanisms of protection. After …
Diagnosis of childhood tuberculosis and host RNA expression in Africa
ST Anderson, M Kaforou, AJ Brent… - … England Journal of …, 2014 - Mass Medical Soc
Background Improved diagnostic tests for tuberculosis in children are needed. We
hypothesized that transcriptional signatures of host blood could be used to distinguish …
hypothesized that transcriptional signatures of host blood could be used to distinguish …
Host-directed therapy targeting the Mycobacterium tuberculosis granuloma: a review
Infection by the intracellular bacterial pathogen Mycobacterium tuberculosis (Mtb) is a major
cause of morbidity and mortality worldwide. Slow progress has been made in lessening the …
cause of morbidity and mortality worldwide. Slow progress has been made in lessening the …
Importance of tuberculosis control to address child survival
Tuberculosis commonly affects young children (< 5 years) in countries that have high rates
of child mortality. 1 The global public health focus to control tuberculosis has traditionally …
of child mortality. 1 The global public health focus to control tuberculosis has traditionally …
Tuberculosis in children with severe acute malnutrition
BJ Vonasek, KK Radtke, P Vaz, WC Buck… - Expert review of …, 2022 - Taylor & Francis
Introduction With growing attention globally to the childhood tuberculosis epidemic after
decades of neglect, and with the burden of severe acute malnutrition (SAM) remaining …
decades of neglect, and with the burden of severe acute malnutrition (SAM) remaining …
Epidemiology of Pediatric Tuberculosis and Factors Associated with Unsuccessful Treatment Outcomes in the Centre Region of Cameroon: A Three‐Year …
TA Vukugah, DA Akoku, MM Tchoupa… - Interdisciplinary …, 2022 - Wiley Online Library
Background. In Cameroon, there are limited data on treatment outcomes of pediatric
tuberculosis (TB). We sought to identify the factors associated with unsuccessful treatment …
tuberculosis (TB). We sought to identify the factors associated with unsuccessful treatment …
Excellent treatment outcomes in children treated for tuberculosis under routine operational conditions in Cape Town, South Africa
M Osman, K Lee, K Du Preez, R Dunbar… - Clinical Infectious …, 2017 - academic.oup.com
Background Tuberculosis (TB) remains a leading cause of death in children globally. It is
recognized that human immunodeficiency virus (HIV) infection increases the risk of …
recognized that human immunodeficiency virus (HIV) infection increases the risk of …
Mortality in South African children and adolescents routinely treated for tuberculosis
BACKGROUND: In South Africa, tuberculosis (TB) is a leading cause of death among those<
20 years of age. We describe changes in TB mortality among children and adolescents in …
20 years of age. We describe changes in TB mortality among children and adolescents in …
Towards early inclusion of children in tuberculosis drugs trials: a consensus statement
S Nachman, A Ahmed, F Amanullah… - The Lancet Infectious …, 2015 - thelancet.com
Children younger than 18 years account for a substantial proportion of patients with
tuberculosis worldwide. Available treatments for paediatric drug-susceptible and drug …
tuberculosis worldwide. Available treatments for paediatric drug-susceptible and drug …