Our understanding of the tuberculosis (TB) epidemic in children is incomplete due to
challenges in diagnosis and reporting. Children have also been largely excluded from …

Children represent both a clinically important population susceptible to tuberculosis and a
key group in whom to study intrinsic and vaccine-induced mechanisms of protection. After …

Background Improved diagnostic tests for tuberculosis in children are needed. We
hypothesized that transcriptional signatures of host blood could be used to distinguish …

Infection by the intracellular bacterial pathogen Mycobacterium tuberculosis (Mtb) is a major
cause of morbidity and mortality worldwide. Slow progress has been made in lessening the …

Tuberculosis commonly affects young children (< 5 years) in countries that have high rates
of child mortality. 1 The global public health focus to control tuberculosis has traditionally …

Introduction With growing attention globally to the childhood tuberculosis epidemic after
decades of neglect, and with the burden of severe acute malnutrition (SAM) remaining …

Background Tuberculosis (TB) remains a leading cause of death in children globally. It is
recognized that human immunodeficiency virus (HIV) infection increases the risk of …

BACKGROUND: In South Africa, tuberculosis (TB) is a leading cause of death among those<
20 years of age. We describe changes in TB mortality among children and adolescents in …

'Decentralize Tuberculosis Services and Engage Communities to Transform lives of
Children with Tuberculosis' was a project set up to strengthen district and community level …

Children younger than 18 years account for a substantial proportion of patients with
tuberculosis worldwide. Available treatments for paediatric drug-susceptible and drug …