Sweating as a heat loss thermoeffector
D Gagnon, CG Crandall - Handbook of clinical neurology, 2018 - Elsevier
In humans, sweating is the most powerful autonomic thermoeffector. The evaporation of
sweat provides by far the greatest potential for heat loss and it represents the only means of …
sweat provides by far the greatest potential for heat loss and it represents the only means of …
CSAHi study-2: validation of multi-electrode array systems (MEA60/2100) for prediction of drug-induced proarrhythmia using human iPS cell-derived cardiomyocytes …
Y Nozaki, Y Honda, H Watanabe, S Saiki… - Regulatory Toxicology …, 2017 - Elsevier
With the aim of reconsidering ICH S7B and E14 guidelines, a new in vitro assay system has
been subjected to worldwide validation to establish a better prediction platform for potential …
been subjected to worldwide validation to establish a better prediction platform for potential …
The roles of the Na+/K+‐ATPase, NKCC, and K+ channels in regulating local sweating and cutaneous blood flow during exercise in humans in vivo
Abstract Na+/K+‐ATP ase has been shown to regulate the sweating and cutaneous vascular
responses during exercise; however, similar studies have not been conducted to assess the …
responses during exercise; however, similar studies have not been conducted to assess the …
Individual variations in nitric oxide synthase‐dependent sweating in young and older males during exercise in the heat: role of aerobic power
We evaluated the association between aerobic power (defined by peak oxygen
consumption; VO 2peak) and the contribution of nitric oxide synthase (NOS) to the sweating …
consumption; VO 2peak) and the contribution of nitric oxide synthase (NOS) to the sweating …
Effect of acute melatonin administration on physiological response to prolonged exercise
A Souissi, N Yousfi, R Dabboubi, G Aloui… - Biological Rhythm …, 2020 - Taylor & Francis
Exogenous melatonin supplementation may enhance endurance performance because of
its pre-cooling effect. The present study aimed to evaluate the effect of acute melatonin …
its pre-cooling effect. The present study aimed to evaluate the effect of acute melatonin …
Thermoregulatory and cardiovasculareffects of capsaicin application on human skin during dynamic exercise to temperate and warm conditions
Thermoregulatory and cardiovascular responses during cycling in temperate and warm
environments without and with application of capsaicin on the skin were investigated. We …
environments without and with application of capsaicin on the skin were investigated. We …
Transdermal iontophoretic application of l-NAME is available in sweating research induced by heat stress in young healthy adults
Y Okamoto, J Otsuka, M Aoki, T Amano - Nitric Oxide, 2023 - Elsevier
Iontophoretic transdermal administration of N G-nitro-l-arginine methyl ester hydrochloride [l-
NAME, a nitric oxide synthase (NOS) inhibitor] has been used as a non-invasive evaluation …
NAME, a nitric oxide synthase (NOS) inhibitor] has been used as a non-invasive evaluation …
No effect of ascorbate on cutaneous vasodilation and sweating in older men and those with type 2 diabetes exercising in the heat
Aging and chronic disease such as type 2 diabetes (T2D) are associated with impairments
in the body's ability to dissipate heat. To reduce the risk of heat‐related injuries in these heat …
in the body's ability to dissipate heat. To reduce the risk of heat‐related injuries in these heat …
Serum, interstitial and sweat ATP in humans exposed to heat stress: Insights into roles of ATP in the heat loss responses
N Fujii, Y Tanabe, T Amano… - Clinical Physiology …, 2023 - Wiley Online Library
Hyperthermia increases intravascular adenosine triphosphate (ATP) and is associated with
greater hyperthermia‐induced cutaneous vasodilation. Hyperthermia may also increase skin …
greater hyperthermia‐induced cutaneous vasodilation. Hyperthermia may also increase skin …
Fluid replacement modulates oxidative stress-but not nitric oxide-mediated cutaneous vasodilation and sweating during prolonged exercise in the heat
BD McNeely, RD Meade, N Fujii… - American Journal …, 2017 - journals.physiology.org
The roles of nitric oxide synthase (NOS), reactive oxygen species (ROS), and angiotensin II
type 1 receptor (AT1R) activation in regulating cutaneous vasodilation and sweating during …
type 1 receptor (AT1R) activation in regulating cutaneous vasodilation and sweating during …