In primary Sjögren syndrome (pSS), chronic inflammation of exocrine glands results in tissue
destruction and sicca symptoms, primarily of the mouth and eyes. Fatigue, arthralgia and …

Primary Sjögren's syndrome (pSS) is a systemic autoimmune disorder characterised by the
T-cell-mediated hyperactivation of B-cells and cytokine production. The condition may …

CD4+ T cells play fundamental roles in orchestrating immune responses and tissue
homeostasis. However, our inability to associate peptide human leukocyte antigen class-II …

Sjögren's syndrome (SS) is an autoimmune disease characterized by the involvement of
exocrine glands such as the salivary and lacrimal glands. The minor salivary glands, from …

Patients with a history of endometriosis have an increased risk of developing various
autoimmune diseases such as rheumatoid arthritis, ankylosing spondylitis, systemic lupus …

Extraglandular manifestations (EGMs) in primary Sjogren's syndrome (pSS) represent the
clinical expression of the systemic involvement in this disease. EGMs are characterized by a …

Primary Sjogren's syndrome (pSS) is a complex chronic autoimmune disease in which local
tissue damage in exocrine glands is combined with broader systemic involvement across …

Background Several observational studies have explored the associations between
Sjögren's syndrome (SS) and certain cancers. Nevertheless, the causal relationships remain …

Abstract Epstein-Barr Virus (EBV), a dsDNA herpesvirus, is believed to play a significant role
in exacerbating and potentially triggering autoimmune and autoinflammatory maladies …

The improved understanding of the molecular basis of innate immunity have led to the
identification of type I interferons (IFNs), particularly IFN-α, as central mediators in the …