Understanding mechanisms of aging and determinants of life span will help to reduce age-
related morbidity and facilitate healthy aging. Average lifespan has increased over the last …

Introduction 3. Homeopathic medicines as “top-down” nanoparticles 3.1. Overlaps between
homeopathic remedy manufacturing and nanoparticle manufacturing methods 3.2. Basic …

Interest in the heat shock proteins (HSPs), as a natural physiological toolkit of living
organisms, has ranged from their chaperone function in nascent proteins to the remedial …

The heat shock response (HSR) is a crucial biochemical pathway that orchestrates the
resolution of inflammation, primarily under proteotoxic stress conditions. This process hinges …

The advance of inflammasome-mediated SASP from adipose to other tissues promotes
cellular senescence in many other cells of the organism, aggravating obesity-dependent …

Adipose tissue dysregulation has a major role in various human diseases. The peroxisome
proliferator-activated receptor-γ (PPARγ) is a key regulator of adipocyte differentiation and …

The FOXO transcription factor family is a conserved regulator of longevity and the
downstream target of insulin/insulin-like signaling. In Caenorhabditis elegans, the FOXO …

The stem bark of Terminalia arjuna (Roxb.) is used by the Ayurvedic physicians in India for
the treatment of various cardiovascular diseases, collectively referred to as hritroga. It has …

Dietary restriction (DR) is a well-established strategy to increase lifespan and stress
resistance in many eukaryotic species. In addition, individuals fed a restricted diet typically …

Proteome homeostasis, or proteostasis, is essential to maintain cellular fitness and its
disturbance is associated with a broad range of human health conditions and diseases …