Recognition in the domain of molecular chirality: from noncovalent interactions to separation of enantiomers
P Peluso, B Chankvetadze - Chemical Reviews, 2022 - ACS Publications
It is not a coincidence that both chirality and noncovalent interactions are ubiquitous in
nature and synthetic molecular systems. Noncovalent interactivity between chiral molecules …
nature and synthetic molecular systems. Noncovalent interactivity between chiral molecules …
Cyclodextrin-based ocular drug delivery systems: A comprehensive review
Q Wang, A Zhang, L Zhu, X Yang, G Fang… - Coordination Chemistry …, 2023 - Elsevier
Cyclodextrin (CD), a class of cyclic oligosaccharides with an external hydrophilic surface
and a central hydrophobic cavity is recognized as a promising pharmaceutical excipient due …
and a central hydrophobic cavity is recognized as a promising pharmaceutical excipient due …
Pharmaceutical applications of cyclodextrins: basic science and product development
T Loftsson, ME Brewster - Journal of pharmacy and …, 2010 - academic.oup.com
Objectives Drug pipelines are becoming increasingly difficult to formulate. This is punctuated
by both retrospective and prospective analyses that show that while 40% of currently …
by both retrospective and prospective analyses that show that while 40% of currently …
Cyclodextrins as pharmaceutical solubilizers
ME Brewster, T Loftsson - Advanced drug delivery reviews, 2007 - Elsevier
Cyclodextrins are useful functional excipients that have enjoyed widespread attention and
use. The basis for this popularity from a pharmaceutical standpoint, is the ability of these …
use. The basis for this popularity from a pharmaceutical standpoint, is the ability of these …
Cyclodextrins and their pharmaceutical applications
T Loftsson, D Duchene - International journal of pharmaceutics, 2007 - Elsevier
Cyclodextrins were first described by Villiers in 1891. Schardinger laid the foundation of the
cyclodextrin chemistry in 1903–1911 and identified both α-and β-cyclodextrin. In the 1930s …
cyclodextrin chemistry in 1903–1911 and identified both α-and β-cyclodextrin. In the 1930s …
Self-association of cyclodextrins and cyclodextrin complexes
T Loftsson, M Másson, ME Brewster - Journal of pharmaceutical sciences, 2004 - Elsevier
Cyclodextrins are useful functional excipients, which are being used in an ever-increasing
way to camouflage undesirable pharmaceutical characteristics, especially poor aqueous …
way to camouflage undesirable pharmaceutical characteristics, especially poor aqueous …
Self-assembled cyclodextrin aggregates and nanoparticles
Cyclodextrins (CDs) are widely used as enabling pharmaceutical excipients, mainly as
solubilizing complexing agents. CDs are cyclic oligosaccharides with hydrophilic outer …
solubilizing complexing agents. CDs are cyclic oligosaccharides with hydrophilic outer …
Self-assembly of cyclodextrins and their complexes in aqueous solutions
A Ryzhakov, T Do Thi, J Stappaerts, L Bertoletti… - Journal of …, 2016 - Elsevier
Cyclodextrins (CDs) are enabling pharmaceutical excipients that can be found in numerous
pharmaceutical products worldwide. Because of their favorable toxicologic profiles, CDs are …
pharmaceutical products worldwide. Because of their favorable toxicologic profiles, CDs are …
The complexation efficiency
T Loftsson, D Hreinsdóttir, M Másson - Journal of Inclusion Phenomena …, 2007 - Springer
Studies have shown that cyclodextrins form both inclusion and non-inclusion complexes and
that several different types of complexes can coexist in aqueous solutions. In addition, both …
that several different types of complexes can coexist in aqueous solutions. In addition, both …
Pharmaceutical applications of cyclodextrins and their derivatives
Cyclodextrins (CDs) are abundantly explored in the field of medicines for the design of
various types of drug delivery systems. They are cyclic oligosaccharides carrying α (1, 4) …
various types of drug delivery systems. They are cyclic oligosaccharides carrying α (1, 4) …