[HTML][HTML] Human genetic and immunological determinants of critical COVID-19 pneumonia

Q Zhang, P Bastard, A Cobat, JL Casanova - Nature, 2022 - nature.com
SARS-CoV-2 infection is benign in most individuals but, in around 10% of cases, it triggers
hypoxaemic COVID-19 pneumonia, which leads to critical illness in around 3% of cases …

[HTML][HTML] Immunology of SARS-CoV-2 infection in children

J Chou, PG Thomas, AG Randolph - Nature immunology, 2022 - nature.com
Children and adolescents exhibit a broad range of clinical outcomes from SARS-CoV-2
infection, with the majority having minimal to mild symptoms. Additionally, some succumb to …

Risk factors for severe and critically ill COVID‐19 patients: a review

Y Gao, M Ding, X Dong, J Zhang, A Kursat Azkur… - Allergy, 2021 - Wiley Online Library
The pandemic of coronavirus disease 2019 (COVID‐19), caused by the severe acute
respiratory syndrome coronavirus 2 (SARS‐CoV‐2), has caused an unprecedented global …

Rapid generation of durable B cell memory to SARS-CoV-2 spike and nucleocapsid proteins in COVID-19 and convalescence

GE Hartley, ESJ Edwards, PM Aui, N Varese… - Science …, 2020 - science.org
Lasting immunity following SARS-CoV-2 infection is questioned because serum antibodies
decline in convalescence. However, functional immunity is mediated by long-lived memory T …

[PDF][PDF] SARS-CoV-2 infections in children: Understanding diverse outcomes

P Brodin - Immunity, 2022 - cell.com
SARS-CoV-2 infections mostly lead to mild or even asymptomatic infections in children, but
the reasons for this are not fully understood. More efficient local tissue responses, better …

COVID-19 in patients with primary and secondary immunodeficiency: the United Kingdom experience

AM Shields, SO Burns, S Savic, AG Richter… - Journal of Allergy and …, 2021 - Elsevier
Background As of November 2020, severe acute respiratory syndrome coronavirus 2 has
resulted in 55 million infections worldwide and more than 1.3 million deaths from …

Immunogenicity of Pfizer-BioNTech COVID-19 vaccine in patients with inborn errors of immunity

D Hagin, T Freund, M Navon, T Halperin, D Adir… - Journal of Allergy and …, 2021 - Elsevier
Background In mid-December 2020, Israel started a nationwide mass vaccination campaign
against coronavirus disease 2019 (COVID-19). In the first few weeks, medical personnel …

COVID-19 convalescent plasma for the treatment of immunocompromised patients: a systematic review and meta-analysis

JW Senefeld, M Franchini, C Mengoli… - JAMA network …, 2023 - jamanetwork.com
Importance Patients who are immunocompromised have increased risk for morbidity and
mortality associated with coronavirus disease 2019 (COVID-19) because they less …

COVID‐19 in children. II: pathogenesis, disease spectrum and management

AR Howard‐Jones, DP Burgner… - … of paediatrics and …, 2022 - Wiley Online Library
The global disruption of the COVID‐19 pandemic has impacted the life of every child either
directly or indirectly. This review explores the pathophysiology, immune response, clinical …

[HTML][HTML] SARS-CoV-2 infection in pediatric population before and during the Delta (B. 1.617. 2) and Omicron (B. 1.1. 529) variants era

H Khemiri, K Ayouni, H Triki, S Haddad-Boubaker - Virology journal, 2022 - Springer
Background COVID-19, the coronavirus disease that emerged in December 2019, caused
drastic damage worldwide. At the beginning of the pandemic, available data suggested that …