The past decade has seen several critical advances in our understanding of hypothalamic–
pituitary–adrenal (HPA) axis regulation. Homeostatic physiological circuits need to integrate …

Objective: This clinical practice guideline addresses the diagnosis and treatment of primary
adrenal insufficiency. Participants: The Task Force included a chair, selected by The Clinical …

Objective: To formulate clinical practice guidelines for hormonal replacement in
hypopituitarism in adults. Participants: The participants include an Endocrine Society …

Cushing's syndrome is a serious endocrine disease caused by chronic, autonomous, and
excessive secretion of cortisol. The syndrome is associated with increased mortality and …

Adrenal insufficiency (AI) is a condition characterized by an absolute or relative deficiency of
adrenal cortisol production. Primary AI (PAI) is rare and is caused by direct adrenal failure …

Objective This guideline will provide the practicing endocrinologist with an approach to the
assessment and treatment of dyslipidemia in patients with endocrine diseases, with the …

Adrenal insufficiency continues to be a challenge for patients, their physicians, and
researchers. During the past decade, long-term studies have shown increased mortality and …

Mechanisms of Glucocorticoid-Induced Insulin Resistance - Endocrinology and Metabolism
Clinics Skip to Main Content Skip to Main Menu Advertisement Endocrinology and …

Hypopituitarism refers to deficiency of one or more hormones produced by the anterior
pituitary or released from the posterior pituitary. Hypopituitarism is associated with excess …

Chronic excessive activation of glucocorticoid receptors induces obesity, insulin resistance,
glucose intolerance, dyslipidaemia and hypertension. Subtle abnormalities of the …