The composition and function of microbes harbored in the human gastrointestinal lumen
have been underestimated for centuries because of the underdevelopment of nucleotide …

I am deeply honored to be invited to write this scientific autobiography. As a physician-
scientist, pediatrician, molecular biologist, and geneticist, I have authored/coauthored more …

Metals such as Fe, Cu, Zn, and Mn are essential trace nutrients for all kingdoms of life,
including microbial pathogens and their hosts. During infection, the mammalian host …

Background Myeloid leukemia is associated with reduced serum zinc and increased
intracellular zinc. Our previous studies found that zinc depletion by TPEN induced apoptosis …

Fish can regulate their Zn body bioaccumulation, but the mechanisms and physiological
responses at the organ level are still largely unknown. In the present study, we exposed the …

Background Spinal cord injury (SCI) is a devastating disease that results in permanent
paralysis. Currently, there is no effective treatment for SCI, and it is important to identify …

Objective The aim of the study is to investigate the function and mechanism of Zinc
Gluconate (ZG) on intestinal mucosal barrier damage in antibiotics and Lipopolysaccharide …

Proton-pump inhibitors (PPI), eg, omeprazole or pantoprazole, are the most widely used
drugs for various gastrointestinal diseases. However, more and more side effects, especially …

Zrt-/Irt-like protein 8 (ZIP8) is a recently identified divalent metal cation transporter expressed
ubiquitously throughout the body. Tissue distribution profiles have indicated that ZIP8 is …