The inflammatory bowel diseases (IBD) comprise complex genetic disorders, with multiple
contributing genes. Linkage studies have implicated several genomic regions as likely …

Standard of care for ulcerative colitis involves long‐term pharmacotherapy or colectomy.
Approximately 20% to 30% of patients eventually require a colectomy because patients …

OBJECTIVE: To determine the characteristics of inflammatory bowel disease (IBD) in young
patients. STUDY DESIGN: Uniform data were collected from a cohort of patients with IBD …

Objective. Chronic granulomatous disease (CGD) is a rare disorder of phagocyte oxidative
metabolism. In addition to infectious complications, granulomatous lesions often involve …

Many human genes have adapted to the constant threat of exposure to infectious agents;
according to the “hygiene hypothesis,” lack of exposure to parasites in modern settings …

Several papers report that the colon is one of the tissues regulated by estrogen receptor
(ER) β. To better understand the physiological role of ERβ in colonic tissue, we have …

The similarities between adult and pediatric patients diagnosed with inflammatory bowel
disease (IBD) are obvious and numerous. In this article the authors describe some of the IBD …

Background Early-onset (EO) pediatric inflammatory bowel diseases (IBD) seem to be more
extensive than those with a later onset. To test this hypothesis, we examined the phenotype …

Background Mesenchymal stromal cells ability to reset immune functionalities may be useful
in Crohn's disease. Aim To perform a first‐in‐human phase 1 safety clinical trial of …

Background The incidence of inflammatory bowel disease (IBD) has been increasing in
Western countries. In younger people, Crohn's disease (CD) predominates over ulcerative …