Updates on the Role of Probiotics against Different Health Issues: Focus on Lactobacillus

A Un-Nisa, A Khan, M Zakria, S Siraj, S Ullah… - International Journal of …, 2022 - mdpi.com
This review article is built on the beneficial effects of Lactobacillus against different diseases,
and a special focus has been made on its effects against neurological disorders, such as …

Aberrant energy metabolism in Alzheimer's disease

L Yu, J Jin, Y Xu, X Zhu - Journal of translational internal medicine, 2022 - degruyter.com
To maintain energy supply to the brain, a direct energy source called adenosine
triphosphate (ATP) is produced by oxidative phosphorylation and aerobic glycolysis of …

Neuroprotective effects of osmotin in Parkinson's disease-associated pathology via the AdipoR1/MAPK/AMPK/mTOR signaling pathways

JS Park, K Choe, HJ Lee, TJ Park, MO Kim - Journal of biomedical science, 2023 - Springer
Background Parkinson's disease (PD) is the second most frequent age-related
neurodegenerative disorder and is characterized by the loss of dopaminergic neurons. Both …

Alpha-linolenic acid impedes cadmium-induced oxidative stress, neuroinflammation, and neurodegeneration in mouse brain

SI Alam, MW Kim, FA Shah, K Saeed, R Ullah, MO Kim - Cells, 2021 - mdpi.com
Alpha-Linolenic acid (ALA), an omega-3 polyunsaturated fatty acid, is extracted from plant
sources and has been shown to be one of the anti-inflammatory and antioxidant agents …

Cycloastragenol, a triterpenoid saponin, regulates oxidative stress, neurotrophic dysfunctions, neuroinflammation and apoptotic cell death in neurodegenerative …

M Ikram, MH Jo, K Choe, A Khan, S Ahmad, K Saeed… - Cells, 2021 - mdpi.com
Here, we have unveiled the effects of cycloastragenol against Aβ (Amyloid-beta)-induced
oxidative stress, neurogenic dysfunction, activated mitogen-activated protein (MAP) kinases …

Neuroprotective effects of nicotinamide against mptp-induced parkinson's disease in mice: impact on oxidative stress, neuroinflammation, nrf2/ho-1 and tlr4 signaling …

IU Rehman, A Khan, R Ahmad, K Choe, HY Park… - Biomedicines, 2022 - mdpi.com
Nicotinamide (NAM) is the amide form of niacin and an important precursor of nicotinamide
adenine dinucleotide (NAD), which is needed for energy metabolism and cellular functions …

Lupeol Treatment Attenuates activation of glial cells and oxidative-stress-mediated neuropathology in mouse model of traumatic brain injury

R Ahmad, A Khan, IU Rehman, HJ Lee, I Khan… - International journal of …, 2022 - mdpi.com
Traumatic brain injury (TBI) signifies a major cause of death and disability. TBI causes
central nervous system (CNS) damage under a variety of mechanisms, including protein …

Antioxidative and anti-inflammatory effects of kojic acid in Aβ-induced mouse model of Alzheimer's disease

A Khan, TJ Park, M Ikram, S Ahmad, R Ahmad… - Molecular …, 2021 - Springer
Alzheimer's disease (AD) is a common cause of dementia that is clinically characterized by
the loss of memory and cognitive functions. Currently, there is no specific cure for the …

Aerobic exercise alleviates abnormal autophagy in brain cells of APP/PS1 mice by upregulating AdipoR1 levels

Y Jian, S Yuan, J Yang, Y Lei, X Li, W Liu - International journal of …, 2022 - mdpi.com
Abnormalities in autophagy are associated with Alzheimer's disease (AD)-like lesions.
Studies have shown that exercise can significantly improve AD autophagy abnormalities, but …

[HTML][HTML] Establishing co-culture blood–brain barrier models for different neurodegeneration conditions to understand its effect on BBB integrity

JS Park, K Choe, A Khan, MH Jo, HY Park… - International Journal of …, 2023 - mdpi.com
The blood–brain barrier (BBB) is a functional interface that provides selective permeability,
protection from toxic substances, transport of nutrients, and clearance of brain metabolites …