Vaccination remains our main defence against influenza, which causes substantial annual
mortality and poses a serious pandemic threat. Influenza virus evades immunity by rapidly …

Poliovirus (PV), the virus that causes both acute poliomyelitis and post-polio syndrome, is
classified within the Enterovirus C species, and there are three wild PV serotypes: WPV1 …

In 2022, Malawi and Mozambique reported WPV1 cases linked to a Pakistan strain, the first
WPV1 cases in the African region since 2016. During 2022 and 2023, Afghanistan and …

During January 2021–December 2022, 76 cVDPV type 2 outbreaks occurred in 42
countries. Since 2020, the numbers of paralytic cases and new emergences have declined …

We report an emergence and increase in poliovirus type 2 detection via routine wastewater
surveillance in three non-overlapping regions in the Jerusalem region, Israel, between April …

Background Novel oral poliovirus vaccine type 2 (nOPV2) was developed by modifying the
Sabin strain to increase genetic stability and reduce risk of seeding new circulating vaccine …

Despite their fundamental role in resolving viral infections, our understanding of how
polyclonal neutralizing antibody responses target non-enveloped viruses remains limited …

Abstract When the Global Polio Eradication Initiative began in 1988, wild poliovirus (WPV)
transmission was reported in 125 countries. Since 2017, Afghanistan and Pakistan remain …

Abstract In May 2016, the Global Polio Eradication Initiative (GPEI) coordinated the
cessation of all use of type 2 oral poliovirus vaccine (OPV2), except for emergency outbreak …

Two WPV1 cases had been reported in 2022 as of September 30, compared with one case
during the same period in 2021. No type 2 circulating vaccine-derived poliovirus was …